PSEN1 Gene Alzheimer Disease Type 3 NGS Genetic DNA Test
Comprehensive Genetic Testing for Early-Onset Alzheimer’s Disease
The PSEN1 Gene Alzheimer Disease Type 3 NGS Genetic DNA Test represents a breakthrough in neurological genetic testing, specifically designed to identify mutations in the PSEN1 gene that are strongly associated with early-onset familial Alzheimer’s disease. This advanced diagnostic tool provides critical insights for individuals concerned about their genetic risk for developing Alzheimer’s disease before the age of 65.
What Does the PSEN1 Gene Test Measure?
This sophisticated genetic analysis utilizes Next-Generation Sequencing (NGS) technology to comprehensively examine the PSEN1 (Presenilin 1) gene, which plays a crucial role in the production of amyloid precursor protein. The test specifically detects:
- Pathogenic mutations in the PSEN1 gene associated with Alzheimer’s disease type 3
- Genetic variants that increase susceptibility to early-onset dementia
- Inherited patterns of Alzheimer’s disease within families
- Specific nucleotide changes that affect protein function and amyloid processing
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing or concerned about:
- Family history of early-onset Alzheimer’s disease (before age 65)
- Unexplained memory loss or cognitive decline in younger adults
- Multiple family members diagnosed with dementia
- Planning for future healthcare and lifestyle decisions
- Reproductive planning when there’s familial Alzheimer’s history
- Progressive cognitive symptoms including memory impairment, confusion, or personality changes
Significant Benefits of PSEN1 Genetic Testing
Undergoing PSEN1 genetic testing offers numerous advantages for proactive health management:
- Early Risk Assessment: Identify genetic predisposition years before symptoms appear
- Personalized Prevention Strategies: Develop targeted lifestyle and medical interventions
- Family Planning Guidance: Make informed decisions about reproduction and genetic counseling
- Clinical Trial Eligibility: Qualify for early intervention studies and new treatments
- Reduced Diagnostic Uncertainty: Provide clarity for unexplained neurological symptoms
- Comprehensive Genetic Counseling: Professional guidance for result interpretation and family implications
Understanding Your Test Results
Your PSEN1 genetic test results will fall into one of several categories, each with specific implications:
- Positive Result: Indicates the presence of a known pathogenic mutation associated with increased Alzheimer’s disease risk. This result enables proactive monitoring and early intervention strategies.
- Negative Result: No known pathogenic mutations detected, which may provide reassurance but doesn’t eliminate all Alzheimer’s risk factors.
- Variant of Uncertain Significance (VUS): Identifies genetic changes with unknown clinical significance, requiring ongoing monitoring and family studies.
- Carrier Status: Important information for family planning and understanding inheritance patterns.
All results are accompanied by comprehensive genetic counseling to ensure proper understanding and appropriate next steps.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| PSEN1 Gene Alzheimer Disease Type 3 NGS Genetic DNA Test – Discount Price | $500 |
| PSEN1 Gene Alzheimer Disease Type 3 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly offer the PSEN1 Gene Alzheimer Disease Type 3 NGS Genetic DNA Test across our extensive network of testing centers throughout the United States. Our facilities are conveniently located in major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and Illinois metropolitan area
- Houston and Texas Gulf Coast
- Phoenix and Arizona communities
- Philadelphia and Pennsylvania region
- All other major cities nationwide
Take Control of Your Neurological Health Today
Don’t let uncertainty about your genetic risk for Alzheimer’s disease dictate your future. The PSEN1 Gene Alzheimer Disease Type 3 NGS Genetic DNA Test provides the clarity and information needed to make informed healthcare decisions. Our team of genetic specialists and neurologists are ready to support you through every step of the testing process.
Ready to schedule your genetic test? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your neurological health with confidence and precision.
Our comprehensive testing package includes professional genetic counseling, detailed result interpretation, and personalized recommendations based on your specific genetic profile. With a turnaround time of 3-4 weeks and multiple sample collection options (blood, extracted DNA, or FTA card), we make genetic testing accessible and convenient for everyone concerned about familial Alzheimer’s disease risk.
