Phospholipase A2 Receptor Antibody PLA2R Quantitative Test
Understanding the PLA2R Antibody Test
The Phospholipase A2 Receptor Antibody PLA2R Quantitative Test represents a breakthrough in autoimmune kidney disease diagnostics. This sophisticated laboratory analysis detects and measures antibodies directed against the phospholipase A2 receptor, a critical protein found in the glomerular podocytes of the kidneys. The presence of these autoantibodies is strongly associated with primary membranous nephropathy, making this test an essential tool for nephrologists and healthcare providers managing complex kidney conditions.
What Does the Test Measure?
This quantitative immunoassay specifically measures:
- Anti-PLA2R IgG antibodies in serum samples
- Antibody concentration levels to assess disease activity
- Autoimmune response targeting kidney glomerular structures
- Biomarker levels that correlate with disease severity and progression
Clinical Importance and Applications
The PLA2R antibody test has revolutionized the diagnosis and management of membranous nephropathy. Unlike traditional kidney biopsies that provide only a snapshot in time, this blood-based test offers dynamic monitoring capabilities. The quantitative nature of the test allows healthcare providers to track treatment response, predict disease outcomes, and make informed decisions about immunosuppressive therapy.
Who Should Consider This Test?
This diagnostic test is particularly recommended for individuals experiencing:
- Unexplained proteinuria or elevated urine protein levels
- Nephrotic syndrome symptoms including edema and swelling
- Unexplained kidney function decline
- Suspected autoimmune kidney disorders
- Monitoring of known membranous nephropathy cases
- Evaluation of treatment response in autoimmune kidney disease
Key Benefits of PLA2R Antibody Testing
Choosing the Phospholipase A2 Receptor Antibody test provides numerous advantages for patients and healthcare providers:
- Non-invasive Diagnosis: Avoids the need for immediate kidney biopsy in many cases
- Treatment Monitoring: Enables real-time assessment of therapy effectiveness
- Prognostic Value: Helps predict disease course and potential complications
- Early Detection: Identifies autoimmune kidney involvement before significant damage occurs
- Personalized Care: Guides individualized treatment plans based on antibody levels
Understanding Your Test Results
Interpreting PLA2R antibody results requires professional medical expertise, but general guidance includes:
- Positive Results: Indicates active autoimmune response against kidney structures, typically associated with primary membranous nephropathy
- Quantitative Levels: Higher antibody concentrations often correlate with more severe disease activity
- Treatment Response: Decreasing antibody levels typically indicate positive response to immunosuppressive therapy
- Negative Results: May suggest alternative causes of kidney disease or different forms of membranous nephropathy
- Follow-up Testing: Regular monitoring helps track disease progression and treatment effectiveness
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $162 |
| Regular Price | $226 |
Nationwide Accessibility
GGC DNA Diagnostics maintains comprehensive testing facilities across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and Philadelphia. Our network ensures timely sample processing and rapid result delivery to healthcare providers nationwide.
Advanced Testing Methodology
Our PLA2R antibody testing utilizes state-of-the-art Enzyme Immunoassay technology, providing exceptional accuracy and reliability. The testing process involves:
- Highly specific antigen-antibody detection systems
- Automated platforms for consistent, reproducible results
- Rigorous quality control measures at every testing stage
- Expert interpretation by specialized laboratory professionals
Sample Requirements and Processing
For optimal testing accuracy, we require:
- Sample Volume: 3 mL (minimum 1 mL) serum from 1 SST tube
- Shipping: Refrigerated or frozen transport conditions
- Turnaround: Same-day reporting when samples received by 11 am Tuesday or Friday
- Preparation: No special patient preparation needed
Take Control of Your Kidney Health
Early detection and proper management of autoimmune kidney conditions can significantly improve long-term outcomes. The Phospholipase A2 Receptor Antibody test provides critical information that empowers both patients and healthcare providers to make informed decisions about kidney health management.
Ready to schedule your test? Contact our dedicated patient services team today at +1(267) 388-9828 or book your appointment online through our secure patient portal. Our knowledgeable staff will guide you through the testing process and ensure you receive the comprehensive care you deserve.
At GGC DNA Diagnostics, we combine cutting-edge technology with compassionate patient care to deliver exceptional diagnostic services. Trust our expertise for accurate, reliable PLA2R antibody testing and comprehensive kidney health evaluation.
