NAFLD PNPLA3 TM6SF2 Genotyping Test
Comprehensive Genetic Assessment for Non-Alcoholic Fatty Liver Disease
The NAFLD PNPLA3 TM6SF2 Genotyping Test represents a breakthrough in preventive liver health management, offering individuals crucial insights into their genetic predisposition to non-alcoholic fatty liver disease (NAFLD). This sophisticated molecular diagnostic tool examines specific genetic markers that significantly influence liver fat accumulation and disease progression, providing healthcare providers with valuable information for personalized treatment strategies and preventive care planning.
What This Advanced Genetic Test Measures
Our state-of-the-art genotyping test specifically analyzes two critical genetic variants:
- PNPLA3 Gene Variant (rs738409): This specific genetic mutation in the patatin-like phospholipase domain-containing protein 3 gene is strongly associated with increased liver fat content and heightened risk of developing NAFLD, non-alcoholic steatohepatitis (NASH), and liver fibrosis.
- TM6SF2 Gene Variant (rs58542926): The transmembrane 6 superfamily member 2 gene variant affects liver fat metabolism and has been linked to both increased liver fat accumulation and reduced secretion of very-low-density lipoproteins, contributing to NAFLD development.
Who Should Consider This Genetic Liver Assessment
This test is particularly valuable for individuals experiencing:
- Unexplained elevated liver enzymes (ALT, AST) on routine blood tests
- Family history of liver disease or NAFLD
- Metabolic syndrome components including obesity, insulin resistance, or type 2 diabetes
- Evidence of fatty liver on ultrasound or other imaging studies
- Persistent fatigue, abdominal discomfort, or other non-specific liver-related symptoms
- Planning lifestyle interventions and wanting baseline genetic risk assessment
Significant Benefits of Genetic NAFLD Testing
Understanding your genetic predisposition to NAFLD offers numerous advantages:
- Early Risk Identification: Detect genetic susceptibility before significant liver damage occurs
- Personalized Prevention Strategies: Tailor lifestyle interventions based on individual genetic risk profile
- Informed Monitoring: Establish appropriate screening frequency based on genetic risk factors
- Family Planning Insights: Understand potential hereditary risks for family members
- Treatment Guidance: Assist healthcare providers in developing targeted management plans
- Peace of Mind: Gain clarity about your liver health status and risk factors
Understanding Your Test Results
Your genetic test results will provide clear information about your specific genotype for both PNPLA3 and TM6SF2 variants:
- Normal Genotype: Indicates typical genetic risk profile for NAFLD
- Heterozygous Variant: Shows one copy of the risk allele, indicating moderate increased risk
- Homozygous Variant: Reveals two copies of the risk allele, indicating significantly elevated genetic predisposition
It’s important to remember that genetic testing provides risk information, not definitive predictions. Your results should be discussed with a qualified healthcare provider who can interpret them in the context of your overall health, lifestyle factors, and clinical presentation.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $126 |
| Regular Price | $212 |
Nationwide Accessibility
We have conveniently located branches across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our extensive network ensures that quality genetic testing is accessible to patients nationwide.
Take Control of Your Liver Health Today
Don’t wait to understand your genetic risk for non-alcoholic fatty liver disease. Our NAFLD PNPLA3 TM6SF2 Genotyping Test provides the critical information you need to make informed decisions about your liver health. With rapid turnaround times and expert analysis, you’ll receive comprehensive results that can guide your healthcare journey.
Ready to schedule your test? Call our dedicated healthcare line at +1(267) 388-9828 or book your appointment online through our secure patient portal. Our genetic counselors and healthcare professionals are available to answer your questions and help you understand how this test can benefit your specific health situation.
Take the first step toward proactive liver health management. Contact us today to schedule your NAFLD genetic risk assessment and gain valuable insights into your genetic predisposition to liver conditions.
