Maternal Serum Screen 2 Dual Test: Comprehensive First-Trimester Prenatal Screening
Understanding the Maternal Serum Screen 2 Dual Test
The Maternal Serum Screen 2 Dual Test represents a significant advancement in prenatal care, offering expectant mothers a non-invasive method to screen for chromosomal abnormalities during the crucial first trimester of pregnancy. This sophisticated screening tool combines biochemical analysis with maternal factors to provide a comprehensive risk assessment for conditions that could affect fetal development.
Conducted between 9-13 weeks gestation (with the ideal window being 10-13 weeks), this test serves as an essential component of modern obstetric care. By detecting potential issues early in pregnancy, healthcare providers can offer timely interventions and appropriate follow-up care, ensuring the best possible outcomes for both mother and baby.
What the Test Measures and Detects
The Maternal Serum Screen 2 Dual Test specifically analyzes two key pregnancy-associated proteins in the mother’s bloodstream:
Primary Biomarkers Measured:
- PAPP-A (Pregnancy-Associated Plasma Protein A): A protein produced by the placenta that typically increases throughout pregnancy
- Free Beta HCG: The free beta subunit of human chorionic gonadotropin, a hormone produced during pregnancy
Risk Evaluation Components:
- Down syndrome (Trisomy 21) risk assessment
- Trisomy 18 (Edwards syndrome) screening
- Combined risk calculation incorporating maternal age, ultrasound findings, and biochemical markers
The test utilizes advanced Chemiluminescent Immunoassay technology to precisely measure these biomarkers, providing highly accurate results that form the basis for comprehensive risk evaluation.
Who Should Consider This Test
The Maternal Serum Screen 2 Dual Test is recommended for all pregnant women during their first trimester, regardless of age or risk factors. However, certain circumstances make this screening particularly important:
Key Candidates Include:
- Women aged 35 years or older at delivery
- Those with a family history of chromosomal abnormalities
- Previous pregnancy affected by chromosomal disorders
- Abnormal ultrasound findings in current pregnancy
- Women with diabetes or other medical conditions
- IVF pregnancies
- Multiple gestation pregnancies (twins)
- Smokers during pregnancy
Even without specific risk factors, this screening provides valuable baseline information and peace of mind for all expectant mothers.
Benefits of Taking the Maternal Serum Screen 2 Dual Test
Choosing to undergo this prenatal screening offers numerous advantages for both maternal and fetal health:
Comprehensive Benefits:
- Early Detection: Identifies potential issues during the first trimester when intervention options are most effective
- Non-Invasive Procedure: Simple blood draw with no risk to the fetus
- High Accuracy: Advanced technology provides reliable risk assessment
- Same-Day Results: Rapid turnaround for timely decision-making
- Personalized Risk Assessment: Combines multiple factors for individualized results
- Peace of Mind: Reduces anxiety by providing concrete information
- Informed Decision Making: Enables discussions with healthcare providers about next steps
- Cost-Effective: Affordable screening at only $62 USD
Understanding Your Test Results
Interpreting your Maternal Serum Screen 2 Dual Test results requires professional medical guidance, but understanding the basic concepts can help you prepare for discussions with your healthcare provider.
Result Categories:
- Screen Negative: Indicates low risk for the conditions screened – most women receive this result
- Screen Positive: Suggests increased risk, requiring further diagnostic testing
- Borderline Results: May warrant repeat testing or additional monitoring
Important Considerations:
- This is a screening test, not a diagnostic test
- Screen positive results do not confirm a chromosomal abnormality
- Further diagnostic testing (like CVS or amniocentesis) may be recommended
- Your gynecologist will explain results in the context of your specific situation
- False positives and false negatives can occur, though rates are low
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Maternal Serum Screen 2 Dual Test | $62 USD | $70 USD |
Service Details:
- Turnaround Time: Sample collected Monday through Saturday by 9 AM; Same-day results
- Sample Type: 3 mL (1.5 mL minimum) serum from 1 SST
- Sample Handling: Ship refrigerated or frozen
- Required Information: Maternal date of birth, LMP or ultrasound data, number of fetuses, diabetic status, body weight, IVF status, smoking history, and previous Trisomy 21 pregnancy history
- Mandatory: Duly filled Maternal Serum Screen requisition form (Form 11)
Nationwide Availability
We have branches conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards regardless of location.
Take the Next Step for Your Pregnancy Health
Don’t leave your prenatal health to chance. The Maternal Serum Screen 2 Dual Test provides crucial information that can significantly impact your pregnancy journey. With same-day results and affordable pricing, there’s no reason to delay this important screening.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our knowledgeable staff is available to answer your questions and help you take this important step toward a healthy pregnancy.
Trust General Genetics Corporation for accurate, reliable prenatal screening that puts your mind at ease and supports the best possible outcomes for you and your baby.

