Liver Kidney Microsomal LKM Antibody in Dilutions IFA Test
Comprehensive Introduction to LKM Antibody Testing
The Liver Kidney Microsomal LKM Antibody in Dilutions IFA Test represents a sophisticated diagnostic approach for detecting autoimmune liver conditions. This specialized immunopathology examination identifies antibodies that specifically target cytochrome P450 2D6 enzymes present in liver and kidney microsomes. The test’s clinical significance lies in its ability to provide definitive evidence of autoimmune hepatitis type 2, a condition that predominantly affects younger individuals and requires precise diagnostic confirmation for appropriate therapeutic management.
What Does the LKM Antibody Test Measure?
This advanced immunofluorescence assay detects and quantifies LKM-1 antibodies, which are autoantibodies directed against the cytochrome P450 2D6 enzyme system. The test employs serial dilutions to determine antibody titers, providing valuable information about:
- Presence and concentration of LKM-1 autoantibodies
- Antibody titer levels through dilution methodology
- Specific immunofluorescence patterns characteristic of autoimmune hepatitis
- Differentiation between various autoimmune liver disorders
Who Should Consider LKM Antibody Testing?
This diagnostic test is particularly recommended for individuals presenting with:
- Unexplained persistent fatigue and general malaise
- Jaundice or yellowing of the skin and eyes
- Abdominal discomfort or pain in the right upper quadrant
- Elevated liver enzymes (ALT, AST) without clear cause
- Family history of autoimmune disorders
- Suspected autoimmune hepatitis based on clinical presentation
- Young patients with liver inflammation of unknown origin
Clinical Benefits of LKM Antibody Testing
Undergoing LKM antibody testing provides multiple advantages for patient care:
- Accurate Diagnosis: Enables precise identification of autoimmune hepatitis type 2
- Treatment Guidance: Informs appropriate immunosuppressive therapy decisions
- Disease Monitoring: Helps track disease progression and treatment response
- Early Intervention: Facilitates timely treatment before significant liver damage occurs
- Differential Diagnosis: Distinguishes autoimmune conditions from viral hepatitis or metabolic disorders
Understanding Your Test Results
Test results are interpreted by our expert immunopathology team:
- Positive Result: Indicates presence of LKM-1 antibodies, suggesting autoimmune hepatitis type 2
- Negative Result: No detectable LKM antibodies, reducing likelihood of autoimmune hepatitis type 2
- Titer Levels: Higher titers often correlate with more active disease
- Clinical Correlation: Results are interpreted in context of symptoms and other liver function tests
All positive results receive comprehensive review by our gastroenterology specialists to ensure accurate interpretation and appropriate follow-up recommendations.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | Liver Kidney Microsomal LKM Antibody in Dilutions IFA Test |
| Regular Price | $170 USD |
| Discount Price | $112 USD |
| Turnaround Time | Sample Daily by 11 am; Report Next Day |
| Sample Type | 3 mL (1.5 mL min.) serum from 1 SST. Ship refrigerated or frozen. |
| Preparation | No special preparation required |
Nationwide Testing Availability
We maintain comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible testing with consistent quality standards and rapid result delivery.
Schedule Your Test Today
Take the first step toward accurate autoimmune liver disease diagnosis. Our experienced team provides professional testing services with compassionate patient care. Contact us to schedule your LKM Antibody test and receive expert guidance throughout the diagnostic process.
Call or WhatsApp: +1(267) 388-9828
Our dedicated healthcare professionals are available to answer your questions, explain the testing process, and help you book your appointment at your convenience.
