WHRN Gene Deafness Autosomal Recessive Type 31 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Hearing Loss
The WHRN Gene Deafness Autosomal Recessive Type 31 NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for hereditary hearing disorders. This sophisticated genetic analysis utilizes next-generation sequencing technology to identify mutations in the WHRN (Whirlin) gene, which plays a critical role in the development and maintenance of hair cells in the inner ear. These specialized sensory cells are essential for converting sound vibrations into electrical signals that the brain interprets as sound.
What This Test Measures and Detects
This advanced genetic test specifically targets the WHRN gene located on chromosome 9q32, which encodes the whirlin protein crucial for stereocilia organization in cochlear hair cells. The test identifies:
- Pathogenic variants in the WHRN gene associated with autosomal recessive nonsyndromic hearing loss
- Point mutations, insertions, deletions, and splice site variants
- Genetic markers for DFNB31, a specific form of congenital hearing impairment
- Carrier status for individuals with family history of hearing loss
- Compound heterozygous mutations that may cause hearing disorders
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Congenital or early-onset hearing loss without other syndromic features
- Progressive sensorineural hearing impairment starting in childhood
- Family history of autosomal recessive hearing disorders
- Unexplained bilateral hearing loss in infants and children
- Consanguineous parents concerned about genetic hearing conditions
- Individuals planning pregnancy with family history of hearing impairment
Clinical Benefits of WHRN Gene Testing
Undergoing this genetic analysis provides numerous advantages for patients and families:
- Accurate Diagnosis: Confirms genetic basis of hearing loss, eliminating diagnostic uncertainty
- Family Planning Guidance: Enables informed reproductive decisions and genetic counseling
- Early Intervention: Facilitates timely implementation of hearing aids, cochlear implants, or communication strategies
- Prognostic Information: Helps predict progression and severity of hearing impairment
- Differential Diagnosis: Distinguishes between various genetic forms of hearing loss
- Research Contribution: Advances understanding of genetic hearing disorders
Understanding Your Test Results
Your genetic test report will provide comprehensive information about your WHRN gene status:
- Normal Result: No pathogenic variants detected in the WHRN gene
- Carrier Status: One mutated copy identified – typically asymptomatic but important for family planning
- Affected Status: Two mutated copies confirmed – indicates genetic hearing loss
- Variant of Uncertain Significance: Genetic change identified with unknown clinical impact
All results are accompanied by detailed interpretation from our certified genetic counselors, who provide personalized guidance based on your specific genetic findings and family history.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| WHRN Gene Deafness Autosomal Recessive Type 31 NGS Genetic DNA Test | $500 USD | $700 USD |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and many more. Our network of certified genetic testing facilities ensures accessible, reliable service regardless of your location.
Take Control of Your Genetic Health Today
Don’t let uncertainty about hereditary hearing conditions affect your quality of life. Our WHRN Gene Deafness Autosomal Recessive Type 31 NGS Genetic DNA Test provides the clarity you need for informed healthcare decisions. With results available in just 3-4 weeks and multiple sample collection options including blood, extracted DNA, or blood spots on FTA cards, getting tested has never been more convenient.
Ready to schedule your genetic test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic hearing health with confidence and precision.
