TBP Gene Spinocerebellar Ataxia Type 17 Autosomal Dominant NGS Genetic DNA Test
Understanding Spinocerebellar Ataxia Type 17
Spinocerebellar ataxia type 17 (SCA17) is a rare, progressive neurological disorder characterized by degeneration of the cerebellum and other brain regions. This autosomal dominant condition results from mutations in the TBP gene, which encodes the TATA-box binding protein essential for gene transcription regulation. The TBP Gene Spinocerebellar Ataxia Type 17 Autosomal Dominant NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, providing precise identification of the specific genetic abnormalities responsible for this debilitating condition.
What This Test Measures and Detects
Our advanced NGS genetic testing specifically targets:
- Comprehensive analysis of the TBP gene for CAG/CAA repeat expansions
- Detection of abnormal trinucleotide repeat sequences (typically 43-66 repeats in affected individuals)
- Identification of specific mutation patterns associated with SCA17
- Assessment of genetic variations that may influence disease severity and progression
- Evaluation of inheritance patterns for family planning considerations
Who Should Consider This Test
This genetic test is recommended for individuals experiencing:
- Progressive coordination difficulties and balance problems
- Unsteady gait and frequent falls
- Speech difficulties including slurred or slow speech
- Involuntary movements and tremors
- Cognitive decline or dementia symptoms
- Family history of similar neurological symptoms
- Unexplained movement disorders in multiple family members
- Early-onset psychiatric symptoms with movement abnormalities
Clinical Benefits of Genetic Testing
Undergoing the TBP Gene SCA17 test provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out SCA17 with high precision
- Early Intervention: Enables proactive management strategies before significant neurological damage occurs
- Family Planning: Provides crucial information for reproductive decisions with 50% inheritance risk
- Treatment Guidance: Helps neurologists develop targeted symptom management plans
- Prognostic Information: Offers insights into potential disease progression patterns
- Genetic Counseling: Includes professional guidance for understanding results and implications
Understanding Your Test Results
Our comprehensive results interpretation includes:
- Normal Results: TBP gene with normal CAG/CAA repeat length (typically 25-42 repeats)
- Abnormal Results: Expanded CAG/CAA repeats (43-66) indicating SCA17 diagnosis
- Intermediate Range: Results between normal and disease range with uncertain significance
- Genetic Counseling Session: Detailed explanation of results and implications
- Family Risk Assessment: Evaluation of inheritance patterns and family member risks
- Clinical Management Recommendations: Guidance for ongoing neurological care
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | TBP Gene Spinocerebellar Ataxia Type 17 Autosomal Dominant NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and neurological specialists ensures you receive comprehensive care regardless of your location.
Take Control of Your Neurological Health Today
Don’t let uncertainty about neurological symptoms affect your quality of life. The TBP Gene Spinocerebellar Ataxia Type 17 test provides the clarity needed for informed healthcare decisions. Our team of genetic specialists and neurologists is ready to guide you through the testing process with compassion and expertise.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Early detection can make a significant difference in managing neurological conditions effectively.
