SLC39A4 Gene Acrodermatitis Enteropathica NGS Genetic DNA Test
Comprehensive Genetic Testing for Zinc Deficiency Disorders
The SLC39A4 Gene Acrodermatitis Enteropathica NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare inherited metabolic disorders. This advanced test specifically targets mutations in the SLC39A4 gene, which encodes the zinc transporter protein ZIP4 essential for proper zinc absorption and metabolism. Acrodermatitis enteropathica is a serious autosomal recessive condition characterized by severe zinc deficiency that can lead to life-threatening complications if left undiagnosed and untreated.
What This Test Measures and Detects
Our comprehensive NGS genetic analysis examines the complete coding region of the SLC39A4 gene to identify pathogenic variants responsible for acrodermatitis enteropathica. The test specifically detects:
- Missense, nonsense, and frameshift mutations in the SLC39A4 gene
- Small insertions and deletions affecting zinc transporter function
- Splice site variants that disrupt normal gene expression
- Compound heterozygous mutations in autosomal recessive inheritance patterns
Who Should Consider This Genetic Test
This specialized genetic test is recommended for individuals presenting with characteristic symptoms of acrodermatitis enteropathica, including:
- Infants and children with periorificial and acral dermatitis
- Patients with chronic diarrhea and malabsorption symptoms
- Individuals exhibiting alopecia, growth retardation, or failure to thrive
- Those with recurrent skin infections and impaired wound healing
- Patients with neurological symptoms including irritability and emotional disturbances
- Individuals with a family history of zinc deficiency disorders
Key Benefits of Genetic Testing
Undergoing the SLC39A4 genetic test provides numerous clinical advantages:
- Definitive Diagnosis: Confirms genetic basis of symptoms, eliminating diagnostic uncertainty
- Personalized Treatment: Enables targeted zinc supplementation therapy
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates prompt treatment to prevent long-term complications
- Differential Diagnosis: Distinguishes from other dermatological and gastrointestinal conditions
Understanding Your Test Results
Our comprehensive genetic report provides clear interpretation of your results:
- Positive Result: Identifies pathogenic mutations confirming acrodermatitis enteropathica diagnosis, requiring immediate zinc supplementation therapy
- Negative Result: No SLC39A4 mutations detected, suggesting alternative causes for symptoms
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation
- Carrier Status: Identifies individuals with single mutation who may pass condition to offspring
Test Pricing Information
| Test Description | Price (USD) |
|---|---|
| SLC39A4 Gene Acrodermatitis Enteropathica NGS Genetic DNA Test – Discount Price | $500 |
| SLC39A4 Gene Acrodermatitis Enteropathica NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality results regardless of your location.
Take Control of Your Genetic Health
Don’t let uncertainty about zinc deficiency disorders impact your quality of life. Our specialized SLC39A4 genetic testing provides the clarity needed for effective treatment and management. With rapid turnaround times of 3-4 weeks and comprehensive genetic counseling support, we make advanced genetic diagnostics accessible and understandable.
Book your SLC39A4 Gene Acrodermatitis Enteropathica NGS Genetic DNA Test today by calling our genetic specialists at +1(267) 388-9828 or schedule your appointment online. Take the first step toward definitive diagnosis and personalized treatment for zinc metabolism disorders.
