SLC10A2 Gene Bile Acid Malabsorption Primary NGS Genetic DNA Test
Comprehensive Genetic Testing for Primary Bile Acid Malabsorption
The SLC10A2 Gene Bile Acid Malabsorption Primary NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for metabolic disorders. This advanced test specifically targets the SLC10A2 gene, which encodes the apical sodium-dependent bile acid transporter (ASBT) protein crucial for proper bile acid recycling in the digestive system. Primary bile acid malabsorption is a rare genetic condition that disrupts the normal enterohepatic circulation of bile acids, leading to significant gastrointestinal symptoms and nutritional deficiencies.
What This Test Measures and Detects
Our comprehensive NGS genetic test analyzes the complete coding region of the SLC10A2 gene to identify pathogenic variants, including:
- Point mutations affecting bile acid transporter function
- Insertions and deletions disrupting protein structure
- Missense mutations altering amino acid sequences
- Nonsense mutations causing premature stop codons
- Splice site variants affecting mRNA processing
The test utilizes state-of-the-art Next-Generation Sequencing technology, providing high-resolution analysis of the entire SLC10A2 gene with exceptional accuracy and reliability. This comprehensive approach ensures detection of both common and rare genetic variants associated with primary bile acid malabsorption.
Who Should Consider This Genetic Test
This specialized genetic test is recommended for individuals experiencing:
- Chronic watery diarrhea that persists despite dietary changes
- Unexplained abdominal pain and cramping
- Steatorrhea (fatty stools) and malabsorption symptoms
- Nutritional deficiencies despite adequate intake
- Family history of bile acid malabsorption or related metabolic disorders
- Children with failure to thrive and gastrointestinal symptoms
- Patients with suspected congenital diarrhea disorders
Clinical Benefits of Genetic Testing
Undergoing the SLC10A2 genetic test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out primary bile acid malabsorption with genetic certainty
- Personalized Treatment: Guides targeted therapy including bile acid sequestrants
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Symptom Management: Helps develop effective dietary and medical management strategies
- Early Intervention: Enables prompt treatment initiation in pediatric cases
- Differential Diagnosis: Distinguishes primary genetic forms from secondary causes
Understanding Your Test Results
Our comprehensive genetic report provides clear interpretation of your results:
- Positive Result: Indicates presence of pathogenic SLC10A2 gene mutation confirming primary bile acid malabsorption diagnosis
- Negative Result: Suggests absence of detected mutations, though clinical correlation remains important
- Variant of Uncertain Significance: Identifies genetic changes requiring additional clinical evaluation
- Carrier Status: Determines inheritance patterns for family members
All results include detailed clinical implications and recommendations for follow-up care. Our genetic counselors are available to help you understand your results and discuss next steps.
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | SLC10A2 Gene Bile Acid Malabsorption Primary NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation for bile acid malabsorption evaluation
- Genetic counseling session to create detailed family pedigree chart
- Discussion of test implications with healthcare provider
- Understanding of potential outcomes and their clinical significance
Take Control of Your Genetic Health Today
Don’t let unexplained gastrointestinal symptoms control your life. The SLC10A2 Gene Bile Acid Malabsorption Primary NGS Genetic DNA Test provides the answers you need for proper diagnosis and targeted treatment. Our advanced genetic testing technology, combined with expert interpretation and comprehensive support, ensures you receive the highest quality care.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your metabolic health.
Our dedicated team of genetic specialists is ready to guide you through the testing process, answer your questions, and provide the personalized care you deserve. Book your appointment now and discover the power of precision genetic medicine.
