SETX Gene Amyotrophic Lateral Sclerosis Type 4 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Neurological Disorders
The SETX Gene Amyotrophic Lateral Sclerosis Type 4 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise detection of mutations associated with ALS Type 4. This rare hereditary form of amyotrophic lateral sclerosis affects the motor neurons responsible for controlling voluntary muscle movements, leading to progressive degeneration and significant disability.
What Does This Advanced Genetic Test Measure?
Our comprehensive NGS (Next-Generation Sequencing) test specifically targets the SETX (senataxin) gene, which plays a crucial role in RNA processing and DNA repair mechanisms. The test identifies:
- Pathogenic variants in the SETX gene associated with ALS Type 4
- Single nucleotide polymorphisms (SNPs) affecting gene function
- Insertions, deletions, and copy number variations
- Novel mutations that may contribute to disease progression
- Genetic markers indicating increased susceptibility to neurological deterioration
Who Should Consider SETX Gene Testing?
This specialized genetic test is recommended for individuals experiencing:
- Progressive muscle weakness in limbs or facial muscles
- Family history of ALS or related neurological disorders
- Early-onset motor neuron disease symptoms
- Muscle twitching (fasciculations) and cramping
- Difficulty with speech, swallowing, or breathing
- Unexplained coordination problems or balance issues
- Progressive difficulty with fine motor skills
Significant Benefits of Early Genetic Detection
Undergoing SETX gene testing provides numerous advantages for patients and families:
- Early Intervention Opportunities: Identify genetic risk factors before significant symptom progression
- Personalized Treatment Planning: Develop targeted therapeutic approaches based on genetic profile
- Family Planning Guidance: Make informed reproductive decisions with genetic counseling
- Proactive Management: Implement lifestyle modifications and monitoring protocols
- Clinical Trial Eligibility: Access to specialized treatments and research opportunities
- Psychological Preparation: Better emotional and practical preparation for disease progression
Understanding Your Genetic Test Results
Our comprehensive genetic counseling services help you interpret your results with clarity and confidence:
- Positive Result: Indicates the presence of a pathogenic SETX gene mutation. Our genetic counselors will discuss implications, inheritance patterns, and management strategies.
- Negative Result: No known pathogenic mutations detected. However, this doesn’t completely rule out genetic factors, and continued monitoring may be recommended.
- Variant of Uncertain Significance (VUS): Some genetic changes require further research. We provide ongoing updates as scientific knowledge advances.
- Carrier Status: Information about potential inheritance risks for future generations.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Accessibility and Support
We maintain comprehensive testing facilities across the United States, with specialized centers in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to cutting-edge genetic testing regardless of your location.
Take Control of Your Neurological Health Today
Don’t wait for symptoms to progress. Early genetic detection through our SETX Gene Amyotrophic Lateral Sclerosis Type 4 NGS Genetic DNA Test can provide crucial insights for managing your neurological health. Our team of board-certified neurologists and genetic specialists are ready to guide you through every step of the testing process.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Take the first step toward understanding your genetic profile and securing your neurological future.
Note: Test turnaround time is 3-4 weeks. Sample types accepted include blood, extracted DNA, or one drop of blood on FTA card. Pre-test requirements include clinical history documentation and a genetic counseling session to create a comprehensive family pedigree chart.
