POU4F3 Gene Deafness Autosomal Dominant Type 15 NGS Genetic DNA Test
Understanding Hereditary Hearing Loss
Hearing loss affects millions worldwide, with genetic factors playing a significant role in many cases. The POU4F3 Gene Deafness Autosomal Dominant Type 15 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing disorders. This specialized test focuses on identifying mutations in the POU4F3 gene, which is crucial for proper inner ear development and function.
What Does This Test Measure?
Our advanced NGS Genetic DNA Test specifically targets the POU4F3 gene, which encodes a transcription factor essential for hair cell development in the cochlea. The test detects:
- Pathogenic variants in the POU4F3 gene
- Autosomal dominant inheritance patterns
- Specific mutations associated with DFNA15 hearing loss
- Genetic markers for progressive sensorineural hearing impairment
- Risk assessment for hereditary deafness transmission
Who Should Consider This Test?
Clinical Indications and Symptoms
This genetic test is recommended for individuals experiencing:
- Progressive hearing loss beginning in childhood or early adulthood
- Family history of hereditary hearing impairment
- Unexplained sensorineural hearing loss
- Planning pregnancy with family history of deafness
- Children with delayed speech development due to hearing issues
- Patients with bilateral symmetric hearing loss
Benefits of POU4F3 Genetic Testing
Early detection through genetic testing provides numerous advantages:
- Early Intervention: Enables timely hearing rehabilitation and management
- Family Planning: Provides crucial information for genetic counseling
- Personalized Treatment: Guides appropriate hearing aid selection and cochlear implant candidacy
- Proactive Monitoring: Allows for regular audiological assessments
- Peace of Mind: Reduces uncertainty about hereditary risk factors
Understanding Your Test Results
Our comprehensive genetic counseling support helps you interpret results:
- Positive Result: Indicates presence of POU4F3 mutation; consult with ENT specialist and genetic counselor
- Negative Result: No detected mutation; however, other genetic factors may still contribute to hearing loss
- Variant of Uncertain Significance: Requires further evaluation and family studies
- Carrier Status: Important information for family planning decisions
Test Details and Pricing
| Test Feature | Details |
|---|---|
| Test Name | POU4F3 Gene Deafness Autosomal Dominant Type 15 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Preparation
Before testing, we recommend:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and next steps
Nationwide Testing Availability
We have branches across the United States, serving patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art genetic testing facilities ensure consistent, reliable results nationwide.
Take Control of Your Hearing Health
Don’t let uncertainty about hereditary hearing loss affect your quality of life. Our POU4F3 genetic test provides the clarity you need to make informed decisions about your hearing health and family planning.
Ready to schedule your test? Call or WhatsApp us today at +1(267) 388-9828 to book your appointment or speak with our genetic counseling team.
Our experienced ENT specialists and genetic counselors are available to discuss your results and provide personalized recommendations based on your genetic profile. Early detection through genetic testing can significantly impact hearing preservation and management strategies.
