OTOF Gene Deafness Autosomal Recessive Type 9 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Hereditary Hearing Loss
The OTOF Gene Deafness Autosomal Recessive Type 9 NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for hereditary hearing disorders. This advanced genetic screening utilizes state-of-the-art Next Generation Sequencing technology to identify mutations in the OTOF (otoferlin) gene, which plays a critical role in auditory neurotransmission and cochlear function.
What Does This Test Measure and Detect?
This specialized genetic test specifically targets and analyzes the OTOF gene located on chromosome 2p23.3. The test detects:
- Pathogenic variants and mutations in the OTOF gene
- Autosomal recessive inheritance patterns associated with DFNB9 deafness
- Specific genetic alterations affecting otoferlin protein function
- Mutations responsible for prelingual nonsyndromic hearing loss
- Genetic markers for auditory neuropathy spectrum disorder
Who Should Consider This Genetic Test?
This test is recommended for individuals experiencing or at risk for:
- Newborns and infants failing routine hearing screenings
- Children with delayed speech development or language acquisition issues
- Individuals with congenital or early-onset hearing impairment
- Patients diagnosed with auditory neuropathy
- Family members of individuals with confirmed OTOF gene mutations
- Couples with family history of hereditary hearing loss planning pregnancy
- Individuals with unexplained progressive hearing loss
Clinical Benefits of OTOF Gene Testing
Early genetic diagnosis through OTOF gene testing provides numerous clinical advantages:
- Early Intervention: Enables timely implementation of hearing aids, cochlear implants, or communication therapies
- Accurate Diagnosis: Provides definitive genetic confirmation of DFNB9 deafness
- Family Planning: Offers crucial information for genetic counseling and reproductive decisions
- Personalized Treatment: Guides appropriate auditory rehabilitation strategies
- Prognostic Information: Helps predict hearing loss progression and severity
- Educational Planning: Assists in developing appropriate educational support systems
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our certified genetic counselors and medical geneticists:
- Positive Result: Indicates the presence of pathogenic OTOF gene mutations confirming DFNB9 diagnosis
- Negative Result: Suggests OTOF gene mutations are not the cause of hearing loss, requiring further investigation
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring ongoing monitoring
- Carrier Status: Reveals if you carry one copy of a mutated gene without showing symptoms
All positive results include comprehensive genetic counseling to discuss implications, management options, and family testing recommendations.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | OTOF Gene Deafness Autosomal Recessive Type 9 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
| Specialty | ENT Doctor, Genetics Department |
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services for patients throughout the country.
Take Control of Your Hearing Health
Don’t let uncertainty about hereditary hearing loss affect your quality of life. Early genetic diagnosis can make a significant difference in treatment outcomes and family planning decisions. Our team of genetic specialists, ENT doctors, and certified counselors are ready to support you through every step of the testing process.
Ready to schedule your OTOF Gene Deafness Genetic Test? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic hearing health and ensuring the best possible outcomes for you and your family.
Our comprehensive pre-test genetic counseling session includes detailed clinical history assessment and pedigree analysis to provide personalized care and accurate genetic interpretation.
