Oncomine Comprehensive Assay: Advanced Cancer Genetic Testing
Comprehensive Introduction to Cancer Genomic Profiling
The Oncomine Comprehensive Assay represents a revolutionary advancement in cancer diagnostics, utilizing next-generation sequencing (NGS) technology to provide unprecedented insights into tumor genetics. This comprehensive molecular profiling test analyzes 161 cancer-related genes simultaneously, offering clinicians a detailed roadmap of the genetic alterations driving cancer progression. By examining DNA and RNA from tumor tissue samples, this assay delivers critical information that transforms cancer treatment from a one-size-fits-all approach to personalized, precision medicine.
Cancer is fundamentally a genetic disease, with specific mutations and alterations dictating tumor behavior, growth patterns, and treatment responses. The Oncomine Comprehensive Assay addresses this complexity by providing a holistic view of the tumor’s genetic landscape, enabling healthcare providers to make informed decisions about targeted therapies, immunotherapies, and clinical trial eligibility. This comprehensive approach has become increasingly essential in modern oncology practice, where understanding the molecular drivers of cancer can significantly impact treatment outcomes and patient survival.
What the Oncomine Comprehensive Assay Detects
This sophisticated diagnostic tool provides comprehensive analysis across multiple genetic alteration types:
Genetic Mutations and Variations
- Single nucleotide variants (SNVs) across 161 cancer genes
- Small insertions and deletions (indels)
- Copy number variations (CNVs)
- Gene fusions and rearrangements
- RNA expression levels for key biomarkers
Key Cancer Pathways Analyzed
- Cell cycle regulation genes
- DNA damage repair pathways
- Growth factor signaling networks
- Apoptosis regulation mechanisms
- Immune checkpoint markers
- Metabolic pathway genes
The assay’s comprehensive nature ensures that no critical genetic information is overlooked, providing clinicians with a complete molecular profile essential for developing targeted treatment strategies.
Who Should Consider the Oncomine Comprehensive Assay
This advanced genetic testing is particularly beneficial for patients experiencing:
Clinical Indications
- Newly diagnosed advanced or metastatic cancer
- Cancers with unclear primary origin
- Treatment-resistant or recurrent malignancies
- Rare or uncommon cancer subtypes
- Patients seeking targeted therapy options
- Individuals considering immunotherapy treatment
- Patients with family history of hereditary cancer syndromes
Symptom Presentations
- Unexplained weight loss and fatigue
- Persistent pain without clear cause
- Unusual lumps or growths
- Changes in bowel or bladder habits
- Persistent cough or hoarseness
- Unexplained bleeding or bruising
- Skin changes or new moles
Significant Benefits of Comprehensive Genetic Testing
Choosing the Oncomine Comprehensive Assay provides numerous advantages for cancer management:
Personalized Treatment Planning
- Identifies specific targeted therapies matched to genetic alterations
- Determines eligibility for immunotherapy based on biomarker status
- Helps avoid ineffective treatments and unnecessary side effects
- Supports clinical trial matching for novel therapies
Comprehensive Diagnostic Insights
- Provides a complete molecular profile in a single test
- Reduces the need for multiple sequential genetic tests
- Offers insights into treatment resistance mechanisms
- Supports prognosis assessment and disease monitoring
Clinical Decision Support
- Enables evidence-based treatment selection
- Supports multidisciplinary tumor board discussions
- Provides data for personalized cancer care pathways
- Facilitates family cancer risk assessment when appropriate
Understanding Your Test Results
Interpreting Oncomine Comprehensive Assay results requires specialized medical expertise, but here’s general guidance:
Result Categories
- Actionable Mutations: Genetic alterations with approved targeted therapies
- Investigational Targets: Mutations eligible for clinical trials
- Prognostic Markers: Genetic changes affecting disease outcome
- Resistance Mutations: Alterations that may reduce treatment effectiveness
Clinical Implications
- Positive results may indicate eligibility for specific targeted treatments
- Negative results help exclude certain therapy options
- Unexpected findings may reveal hereditary cancer risks
- Complex results often benefit from genetic counseling interpretation
Your healthcare provider will discuss the specific implications of your results and develop a personalized treatment plan based on the comprehensive genetic information provided.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Oncomine Comprehensive Assay | $1900 |
| Discount Price | $1426 |
Test Specifications
- Turnaround Time: 2-3 weeks
- Sample Type: Tumor tissue (paraffin embedded tissue blocks)
- Technology: Next-generation sequencing (NGS)
- Prescription Required: Doctor’s prescription needed (not applicable for surgery, pregnancy, or international travel cases)
Nationwide Availability and Booking
GGC DNA has established comprehensive testing facilities across the United States, ensuring convenient access to the Oncomine Comprehensive Assay in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories maintain the highest standards of quality and accuracy, with certified genetic counselors and oncology specialists available to support your testing journey.
Take the Next Step in Your Cancer Care
Don’t leave your cancer treatment to chance. The Oncomine Comprehensive Assay provides the critical genetic information needed to develop a personalized treatment strategy. Our team is ready to assist you in scheduling your test and answering any questions about the process.
Call or WhatsApp us today at +1(267) 388-9828 to book your Oncomine Comprehensive Assay and take control of your cancer treatment journey with precision genetic insights.
Early genetic profiling can make a significant difference in treatment outcomes. Contact us now to schedule your comprehensive cancer genetic testing and begin your path toward personalized cancer care.
