NTRK3 Gene Fusion Test
Understanding NTRK3 Gene Fusion Testing
The NTRK3 Gene Fusion Test represents a breakthrough in precision oncology, offering targeted insights into cancer genetics that can transform treatment approaches. NTRK3 (Neurotrophic Tyrosine Receptor Kinase 3) is a crucial gene that, when rearranged, can drive cancer development through abnormal protein production. This specialized test utilizes Fluorescence In Situ Hybridization (FISH) technology to detect these genetic rearrangements with exceptional accuracy.
What Does the NTRK3 Test Measure?
The NTRK3 Gene Fusion Test specifically detects:
- Chromosomal rearrangements involving the NTRK3 gene
- Fusion events where NTRK3 combines with partner genes
- Genetic abnormalities that create constitutively active TRK proteins
- Molecular drivers of tumor growth and progression
Who Should Consider NTRK3 Testing?
This test is particularly valuable for patients experiencing:
- Rare or uncommon cancer types where NTRK fusions are more prevalent
- Cancers that have shown resistance to conventional therapies
- Pediatric solid tumors with uncertain treatment pathways
- Metastatic cancers requiring targeted treatment options
- Patients seeking precision medicine approaches to cancer care
Clinical Indications and Symptoms
Consider NTRK3 testing if you have been diagnosed with:
- Infantile fibrosarcoma
- Secretory breast carcinoma
- Congenital mesoblastic nephroma
- Papillary thyroid cancer
- Various soft tissue sarcomas
- Other rare tumor types with potential NTRK involvement
Benefits of NTRK3 Gene Fusion Testing
Undergoing NTRK3 testing provides numerous advantages:
- Targeted Treatment Guidance: Identifies eligibility for TRK inhibitor therapies
- Personalized Medicine: Enables customized treatment plans based on genetic profile
- Improved Outcomes: Patients with NTRK fusions often respond exceptionally well to targeted therapies
- Comprehensive Analysis: Provides detailed genetic information for informed decision-making
- Future Planning: Helps guide long-term treatment strategies and monitoring approaches
Test Methodology and Technology
Our NTRK3 testing employs advanced FISH technology, which:
- Uses fluorescent probes to visualize gene rearrangements
- Provides high sensitivity and specificity for detection
- Works effectively with paraffin-embedded tissue samples
- Delivers reliable results for clinical decision-making
- Complements other molecular testing approaches
Understanding Your Test Results
Your NTRK3 test results will fall into one of these categories:
Positive Result
A positive result indicates the presence of an NTRK3 gene fusion, suggesting:
- Potential eligibility for TRK inhibitor therapies
- Specific molecular drivers of your cancer
- Opportunities for targeted treatment approaches
- Discussion points for your oncology team
Negative Result
A negative result means no NTRK3 fusion was detected, indicating:
- Alternative treatment approaches may be more appropriate
- Other genetic testing might be recommended
- Conventional therapies remain viable options
- Continued monitoring and evaluation are important
Inconclusive Result
In some cases, results may be inconclusive due to:
- Insufficient tumor tissue sample
- Technical limitations of the testing process
- Sample quality issues
- Repeat testing may be recommended
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $226 |
| Regular Price | $300 |
| Turnaround Time | 7-8 days |
| Sample Type | Tumor Tissue (Paraffin embedded blocks) |
Pre-Test Instructions
Important considerations before testing:
- Doctor’s prescription required for testing
- Prescription not applicable for surgery cases
- Prescription not applicable during pregnancy
- Prescription not applicable for international travel planning
- Consult with your healthcare provider for specific preparation requirements
Nationwide Testing Availability
GGC DNA provides comprehensive NTRK3 testing services across the United States, with convenient locations in:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and the Midwest region
- Houston and Texas metropolitan areas
- Phoenix and Arizona locations
- All major US cities and metropolitan regions
Take the Next Step in Your Cancer Care Journey
Don’t leave your treatment options to chance. The NTRK3 Gene Fusion Test could unlock targeted therapy opportunities that conventional approaches might miss. Our experienced genetic counselors and oncology specialists are ready to guide you through the testing process and help interpret your results within the context of your overall treatment plan.
Book Your NTRK3 Test Today
Ready to explore precision medicine options for your cancer treatment? Contact our dedicated team to schedule your NTRK3 Gene Fusion Test:
Call or WhatsApp: +1(267) 388-9828
Our genetic specialists are available to answer your questions, discuss testing requirements, and help you take the first step toward personalized cancer care. With rapid 7-8 day turnaround times and comprehensive result interpretation, we’re committed to providing the genetic insights you need for informed treatment decisions.
