NT5C2 Gene SPG45 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Spastic Paraplegia
The NT5C2 Gene SPG45 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise detection of mutations responsible for hereditary spastic paraplegia type 45 (SPG45). This sophisticated genetic analysis provides critical insights for patients experiencing progressive neurological symptoms and helps healthcare providers develop targeted treatment strategies.
What This Advanced Genetic Test Measures
Our NT5C2 Gene SPG45 test utilizes next-generation sequencing (NGS) technology to comprehensively analyze the NT5C2 gene, which encodes the 5′-nucleotidase cytosolic II enzyme. This test specifically identifies:
- Point mutations and single nucleotide variants in the NT5C2 gene
- Insertions and deletions affecting gene function
- Copy number variations and structural abnormalities
- Pathogenic variants associated with SPG45 inheritance patterns
Who Should Consider NT5C2 Genetic Testing?
This specialized genetic test is recommended for individuals experiencing:
- Progressive muscle stiffness and spasticity in lower limbs
- Difficulty walking or abnormal gait patterns
- Family history of hereditary spastic paraplegia
- Unexplained progressive weakness in legs
- Early-onset neurological symptoms without clear diagnosis
- Children showing developmental delays with spasticity
Significant Benefits of NT5C2 Genetic Testing
Undergoing NT5C2 Gene SPG45 testing provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out SPG45 with high precision
- Personalized Treatment: Enables targeted therapeutic approaches
- Family Planning: Provides crucial information for genetic counseling
- Early Intervention: Facilitates timely management strategies
- Prognostic Information: Helps predict disease progression
- Research Contribution: Advances understanding of neurological disorders
Understanding Your Test Results
Our comprehensive genetic report includes detailed interpretation of your NT5C2 gene analysis:
- Positive Result: Indicates presence of pathogenic NT5C2 mutation associated with SPG45
- Negative Result: No disease-causing mutations detected in the NT5C2 gene
- Variant of Uncertain Significance: Genetic changes with unclear clinical impact
- Carrier Status: Information about inheritance patterns for family planning
All results are accompanied by detailed explanations and recommendations for follow-up care with neurologists and genetic counselors.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | NT5C2 Gene SPG45 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Methodology | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your NT5C2 Gene SPG45 test, we recommend:
- Complete clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and next steps
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic testing facilities ensures accessible, reliable testing nationwide.
Take Control of Your Neurological Health
Don’t let uncertainty about hereditary spastic paraplegia affect your quality of life. Our NT5C2 Gene SPG45 NGS Genetic DNA Test provides the clarity you need for informed healthcare decisions. Early genetic diagnosis can significantly impact treatment outcomes and family planning considerations.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
Take the first step toward understanding your genetic health and managing hereditary neurological conditions effectively. Our comprehensive NT5C2 testing provides the answers you need for better neurological care and improved quality of life.
