NDUFAF3 Gene Leigh Syndrome NGS Genetic DNA Test
Comprehensive Genetic Testing for Neurological Disorders
The NDUFAF3 Gene Leigh Syndrome NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, specifically designed to identify mutations in the NDUFAF3 gene that cause Leigh syndrome. This progressive neurodegenerative disorder primarily affects the central nervous system and is characterized by developmental regression, movement disorders, and respiratory problems. Our advanced next-generation sequencing technology provides unparalleled accuracy in detecting genetic variants responsible for this devastating condition.
What Does This Test Measure?
This specialized genetic test specifically targets and analyzes the NDUFAF3 gene using sophisticated next-generation sequencing technology. The test detects:
- Pathogenic variants and mutations in the NDUFAF3 gene
- Single nucleotide polymorphisms (SNPs) associated with Leigh syndrome
- Insertions, deletions, and copy number variations
- Mitochondrial complex I assembly factor deficiencies
- Autosomal recessive inheritance patterns
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with symptoms suggestive of Leigh syndrome or mitochondrial disorders:
- Infants and children showing developmental regression
- Patients with unexplained neurological deterioration
- Individuals with movement disorders, ataxia, or dystonia
- Those with respiratory chain complex I deficiency
- Family members of diagnosed Leigh syndrome patients
- Individuals with elevated lactate levels in blood or cerebrospinal fluid
- Patients with characteristic brain MRI findings of bilateral basal ganglia lesions
Key Benefits of NDUFAF3 Genetic Testing
- Accurate Diagnosis: Provides definitive genetic confirmation of Leigh syndrome
- Family Planning: Enables informed reproductive decisions for at-risk families
- Early Intervention: Facilitates timely management and treatment strategies
- Genetic Counseling: Comprehensive pedigree analysis and inheritance pattern assessment
- Research Contribution: Advances understanding of mitochondrial disorders
Understanding Your Test Results
Our genetic specialists provide detailed interpretation of your NDUFAF3 test results:
- Positive Result: Indicates presence of pathogenic NDUFAF3 mutations confirming Leigh syndrome diagnosis
- Negative Result: Suggests absence of detectable NDUFAF3 mutations but doesn’t rule out other genetic causes
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals with single copy mutations who may pass the condition to offspring
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | NDUFAF3 Gene Leigh Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Specialty | Neurologist |
| Department | Genetics |
| Method | NGS Technology |
| Disease Type | Neurological Disorders |
Pre-Test Requirements
Before scheduling your NDUFAF3 genetic test, please ensure:
- Complete clinical history of the patient
- Genetic counseling session to create detailed family pedigree chart
- Documentation of affected family members with similar symptoms
- Previous neurological evaluations and test results
Nationwide Testing Availability
We have conveniently located branches across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art genetic testing facilities ensure consistent quality and rapid processing regardless of location.
Take Control of Your Genetic Health Today
Don’t let uncertainty about neurological symptoms affect your quality of life. Our expert team of genetic counselors and neurologists are ready to provide comprehensive support and guidance throughout the testing process. Early genetic diagnosis can significantly impact treatment outcomes and family planning decisions.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your NDUFAF3 Gene Leigh Syndrome NGS Genetic DNA Test appointment. Our genetic specialists are available to answer your questions and help you take the next step toward definitive diagnosis and personalized care.
