MTRNR1 Gene Deafness Nonsyndromic Sensorineural Mitochondrial NGS Genetic DNA Test
Comprehensive Genetic Analysis for Hereditary Hearing Loss
The MTRNR1 Gene Deafness Nonsyndromic Sensorineural Mitochondrial NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing conditions. This advanced test specifically targets mutations in the mitochondrial MTRNR1 gene, which plays a critical role in protein synthesis within the mitochondria of auditory cells. Mitochondrial DNA mutations are particularly significant as they follow maternal inheritance patterns, making this test essential for understanding familial hearing loss transmission.
What This Test Measures and Detects
Our comprehensive NGS-based analysis examines the complete mitochondrial MTRNR1 gene sequence to identify:
- Pathogenic variants associated with nonsyndromic sensorineural hearing loss
- Mitochondrial DNA mutations affecting ribosomal RNA function
- Genetic markers for aminoglycoside-induced ototoxicity susceptibility
- Maternal inheritance patterns of hearing impairment
- Early-onset progressive hearing loss genetic risk factors
Who Should Consider This Test
This genetic test is recommended for individuals experiencing:
- Progressive sensorineural hearing loss without other systemic symptoms
- Family history of maternal-line hearing impairment
- Early-onset hearing loss before age 40
- Suspected aminoglycoside antibiotic sensitivity
- Unexplained bilateral hearing deterioration
- Planning pregnancy with family history of genetic hearing conditions
Clinical Benefits and Advantages
Choosing our MTRNR1 genetic testing provides numerous benefits:
- Early Intervention Opportunities: Identify genetic risk before significant hearing loss occurs
- Personalized Treatment Planning: Guide appropriate hearing aid selection and cochlear implant candidacy
- Family Planning Guidance: Understand inheritance risks for future generations
- Medication Safety: Identify susceptibility to aminoglycoside ototoxicity
- Comprehensive Genetic Counseling: Professional interpretation and family risk assessment
Understanding Your Test Results
Our genetic counselors provide detailed interpretation of your results:
- Positive Result: Indicates presence of MTRNR1 mutation with associated hearing loss risk
- Negative Result: No detected mutations in the analyzed MTRNR1 gene regions
- Variant of Uncertain Significance: Genetic changes requiring further clinical correlation
- Carrier Status: Identification of mutation carriers with potential transmission risk
All results include personalized recommendations for hearing conservation, monitoring schedules, and family member testing considerations.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers across all major US cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee. Our certified genetic specialists and ENT doctors provide comprehensive care and counseling throughout the testing process.
Book Your Genetic Test Today
Take the first step toward understanding your genetic hearing health. Our experienced genetic counselors and ENT specialists are ready to guide you through the testing process and provide personalized recommendations based on your results. Call or WhatsApp us at +1(267) 388-9828 to schedule your appointment or discuss your testing options with our genetic specialists.
Note: Pre-test genetic counseling is recommended to discuss family history, testing implications, and result interpretation. Our team provides comprehensive support throughout your genetic testing journey.
