MT-ND2 Gene Mitochondrial Complex I Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Mitochondrial Disorders
The MT-ND2 Gene Mitochondrial Complex I Deficiency NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations responsible for mitochondrial complex I deficiency. This specialized test utilizes next-generation sequencing technology to analyze the MT-ND2 gene, which encodes a critical subunit of complex I in the mitochondrial respiratory chain. Complex I deficiency is among the most common mitochondrial disorders, affecting cellular energy production and leading to multi-system complications.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets the MT-ND2 gene located in mitochondrial DNA, detecting:
- Point mutations and single nucleotide variants in the MT-ND2 gene
- Small insertions and deletions affecting gene function
- Genetic variations that impair complex I assembly and function
- Mutations affecting NADH dehydrogenase activity
- Pathogenic variants associated with Leigh syndrome and other mitochondrial disorders
Who Should Consider This Genetic Test?
This test is recommended for individuals presenting with symptoms suggestive of mitochondrial complex I deficiency, including:
- Unexplained neurological symptoms such as seizures, ataxia, or developmental regression
- Progressive muscle weakness and exercise intolerance
- Vision or hearing problems related to optic atrophy or sensorineural hearing loss
- Metabolic acidosis and lactic acidosis
- Developmental delays in children
- Family history of mitochondrial disorders
- Unexplained multi-organ system involvement
Significant Benefits of Genetic Testing
Undergoing the MT-ND2 Gene Mitochondrial Complex I Deficiency test provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out genetic causes of symptoms
- Personalized Treatment: Enables targeted therapeutic interventions
- Family Planning: Provides recurrence risk information for future pregnancies
- Early Intervention: Facilitates proactive management of symptoms
- Genetic Counseling: Supports informed decision-making for patients and families
- Research Contribution: Advances understanding of mitochondrial diseases
Understanding Your Test Results
Test results are carefully interpreted by our board-certified genetic specialists:
- Positive Result: Indicates the presence of a pathogenic mutation in the MT-ND2 gene, confirming mitochondrial complex I deficiency
- Negative Result: Suggests no detectable mutations in the MT-ND2 gene, though other genetic causes may still be present
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Determines if individuals carry mutations that could affect offspring
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | MT-ND2 Gene Mitochondrial Complex I Deficiency NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Control of Your Genetic Health Today
Don’t let uncertainty about mitochondrial disorders affect your quality of life. Our specialized genetic testing provides the clarity needed for proper diagnosis and management. Contact our genetic counseling team to discuss your testing options and schedule your appointment.
Call or WhatsApp our genetic specialists today: +1(267) 388-9828
Our experienced team is ready to answer your questions, provide comprehensive pre-test genetic counseling, and guide you through the testing process. Early genetic diagnosis can make a significant difference in managing mitochondrial disorders effectively.
