MT-CO3 Gene Cytochrome C Oxidase 3 Deficiency NGS Genetic DNA Test
Comprehensive Genetic Testing for Mitochondrial Disorders
The MT-CO3 Gene Cytochrome C Oxidase 3 Deficiency NGS Genetic DNA Test represents a breakthrough in mitochondrial disease diagnosis, offering precise detection of genetic mutations that affect cellular energy production. This advanced genetic analysis targets the MT-CO3 gene, which encodes a critical subunit of cytochrome c oxidase – the final enzyme in the mitochondrial electron transport chain responsible for cellular respiration and ATP generation.
What This Test Measures and Detects
Our specialized NGS genetic test specifically examines the mitochondrial DNA-encoded MT-CO3 gene for pathogenic variants that disrupt cytochrome c oxidase function. The test identifies:
- Point mutations and small insertions/deletions in the MT-CO3 gene
- Pathogenic variants affecting complex IV assembly and function
- Genetic markers associated with mitochondrial encephalomyopathy
- Inheritance patterns of mitochondrial DNA mutations
- Risk assessment for developing cytochrome c oxidase deficiency
Who Should Consider This Genetic Test
This comprehensive genetic analysis is recommended for individuals presenting with:
- Unexplained muscle weakness and exercise intolerance
- Developmental delays in infants and children
- Neurological symptoms including seizures and ataxia
- Family history of mitochondrial disorders
- Progressive external ophthalmoplegia
- Cardiomyopathy or cardiac conduction defects
- Metabolic acidosis and lactic acidosis
- Failure to thrive in pediatric patients
Clinical Benefits of MT-CO3 Genetic Testing
Undergoing this specialized genetic test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out MT-CO3 gene-related disorders
- Personalized Treatment: Enables targeted therapeutic interventions
- Family Planning: Provides crucial information for reproductive decisions
- Prognostic Information: Helps predict disease progression and severity
- Early Intervention: Facilitates timely management of symptoms
- Genetic Counseling: Supports informed family risk assessment
Understanding Your Test Results
Our comprehensive genetic report provides detailed interpretation of your MT-CO3 gene analysis:
- Positive Result: Indicates the presence of pathogenic MT-CO3 variants requiring specialized neurological care and mitochondrial support
- Negative Result: Suggests typical MT-CO3 gene sequence, though additional testing may be recommended for complex cases
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation and family studies
- Heteroplasmy Levels: Measures the percentage of mutated mitochondrial DNA, crucial for predicting disease severity
Test Pricing and Sample Requirements
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Pre-Test Requirements
Before undergoing the MT-CO3 Gene Deficiency NGS Test, patients should provide:
- Complete clinical history documenting neurological symptoms
- Participation in genetic counseling session
- Detailed pedigree chart of family members affected by mitochondrial disorders
- Informed consent for genetic testing and result interpretation
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities nationwide. Our network of certified genetic counselors and neurological specialists ensures comprehensive care throughout your testing journey.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about mitochondrial disorders affect your health decisions. Our MT-CO3 Gene Cytochrome C Oxidase 3 Deficiency NGS Genetic DNA Test provides the definitive answers you need for proper diagnosis and management. With our discounted price of only $500 USD, advanced genetic testing is more accessible than ever.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our experienced genetic specialists are ready to guide you through the testing process and help you understand your results.
