MSH6 Gene Colorectal Cancer Hereditary Nonpolyposis Type 5 NGS Genetic DNA Test
Comprehensive Genetic Screening for Hereditary Colorectal Cancer Risk
The MSH6 Gene Colorectal Cancer Hereditary Nonpolyposis Type 5 NGS Genetic DNA Test represents a breakthrough in personalized cancer prevention and early detection strategies. This advanced genetic screening specifically targets mutations in the MSH6 gene, which plays a critical role in DNA mismatch repair and is strongly associated with Lynch syndrome – a hereditary condition that significantly increases lifetime risk for colorectal cancer and other malignancies.
What Does This Test Measure and Detect?
This sophisticated genetic analysis utilizes Next-Generation Sequencing (NGS) technology to comprehensively examine the MSH6 gene for pathogenic variants that disrupt normal DNA repair mechanisms. The test specifically identifies:
- Point mutations, insertions, and deletions in the MSH6 gene
- Genetic variants associated with Lynch syndrome (HNPCC type 5)
- Inherited mutations that increase colorectal cancer susceptibility
- DNA mismatch repair deficiencies affecting cellular replication
- Hereditary cancer predisposition markers
Who Should Consider This Genetic Cancer Screening?
This test is particularly recommended for individuals who exhibit specific risk factors or clinical indicators:
- Family History: Individuals with multiple relatives diagnosed with colorectal cancer, especially at young ages
- Early-Onset Cancer: Personal history of colorectal cancer diagnosed before age 50
- Multiple Cancers: Individuals with personal history of multiple Lynch syndrome-associated cancers
- Family Patterns: Families with known Lynch syndrome or MSH6 mutations
- Unexplained Cancer Clusters: Families with unusual cancer patterns across generations
- Preventive Screening: Individuals seeking proactive cancer risk assessment
Clinical Benefits of MSH6 Genetic Testing
Undergoing this comprehensive genetic assessment provides numerous clinical advantages:
- Early Risk Identification: Detect hereditary cancer predisposition before disease development
- Personalized Screening: Implement targeted surveillance protocols based on genetic risk
- Family Risk Assessment: Identify at-risk relatives who may benefit from genetic testing
- Preventive Interventions: Enable proactive medical management and risk reduction strategies
- Treatment Guidance: Inform surgical and therapeutic decisions for affected individuals
- Psychological Preparation: Provide clarity and reduce uncertainty about cancer risk
Understanding Your Test Results
Your genetic test results will fall into one of several categories, each with specific implications:
- Positive Result: Indicates presence of a pathogenic MSH6 mutation, confirming Lynch syndrome diagnosis and requiring enhanced cancer surveillance
- Negative Result: No mutation detected, though family cancer patterns should still guide screening recommendations
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact, requiring ongoing research and family studies
- Benign Variant: Common genetic variations not associated with increased cancer risk
All results are accompanied by comprehensive genetic counseling to ensure proper interpretation and development of personalized management plans.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services for patients nationwide.
Take Control of Your Genetic Health Today
Understanding your hereditary cancer risk is the first step toward proactive health management. The MSH6 Gene Colorectal Cancer Hereditary Nonpolyposis Type 5 NGS Genetic DNA Test provides crucial information that can guide lifelong health decisions and potentially save lives through early detection and prevention.
Ready to schedule your genetic cancer screening? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to discuss your testing options, answer questions about the process, and provide the comprehensive support you need throughout your genetic health journey.
Don’t wait to gain valuable insights into your hereditary cancer risk. Take the proactive step toward personalized cancer prevention and schedule your MSH6 genetic test with GGC DNA today.
