MRAP Gene Glucocorticoid Deficiency Type 2 NGS Genetic DNA Test
Comprehensive Genetic Testing for Rare Metabolic Disorders
The MRAP Gene Glucocorticoid Deficiency Type 2 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare endocrine disorders. This advanced testing methodology provides crucial insights into familial glucocorticoid deficiency type 2, a rare autosomal recessive condition affecting adrenal gland function. Through sophisticated Next-Generation Sequencing technology, our test delivers unparalleled accuracy in identifying genetic mutations that disrupt the body’s cortisol production.
What Does This Test Measure and Detect?
This comprehensive genetic analysis specifically targets the MRAP (Melanocortin 2 Receptor Accessory Protein) gene, which plays a critical role in adrenal cortex development and function. The test identifies:
- Pathogenic variants in the MRAP gene coding regions
- Single nucleotide polymorphisms associated with glucocorticoid deficiency
- Insertion/deletion mutations affecting protein function
- Genetic markers indicating autosomal recessive inheritance patterns
- Specific mutations disrupting ACTH receptor signaling pathways
Who Should Consider This Genetic Test?
This specialized genetic testing is recommended for individuals presenting with symptoms suggestive of adrenal insufficiency or those with family history of endocrine disorders:
- Patients experiencing unexplained fatigue and weakness
- Individuals with recurrent hypoglycemic episodes
- Children showing failure to thrive or growth retardation
- Patients with hyperpigmentation of skin and mucous membranes
- Individuals with salt craving and electrolyte imbalances
- Those with family history of adrenal insufficiency
- Patients with autoimmune conditions affecting endocrine function
- Individuals planning pregnancy with family history of metabolic disorders
Significant Benefits of Genetic Testing
Early genetic diagnosis through MRAP gene testing provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out genetic causes of adrenal insufficiency
- Personalized Treatment: Enables targeted hormone replacement therapy
- Family Planning: Provides crucial information for genetic counseling
- Preventive Care: Helps prevent life-threatening adrenal crises
- Early Intervention: Allows for proactive management of symptoms
- Comprehensive Understanding: Clarifies inheritance patterns for family members
Understanding Your Test Results
Our comprehensive genetic report provides clear, actionable information:
- Positive Result: Indicates presence of MRAP gene mutations; requires endocrinology consultation for hormone replacement therapy
- Negative Result: Suggests alternative causes for symptoms; further endocrine evaluation recommended
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Important for family planning and genetic counseling purposes
All results include detailed interpretation by our certified genetic counselors and recommendations for next steps in clinical management.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | MRAP Gene Glucocorticoid Deficiency Type 2 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing for patients nationwide.
Take Control of Your Health Today
Don’t let uncertainty about genetic conditions affect your quality of life. Our MRAP Gene Glucocorticoid Deficiency Type 2 NGS Genetic DNA Test provides the clarity you need for proper diagnosis and treatment. Early detection can significantly improve outcomes and prevent serious complications.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward comprehensive health management.
Our team of genetic specialists is ready to guide you through the testing process, answer your questions, and provide the support you need for informed healthcare decisions.
