MOGS Gene Glycosylation Disorder Type 2B NGS Genetic DNA Test
Comprehensive Genetic Analysis for Congenital Glycosylation Disorders
The MOGS Gene Glycosylation Disorder Type 2B NGS Genetic DNA Test represents a breakthrough in diagnostic precision for individuals affected by congenital disorders of glycosylation (CDG). This specialized genetic test employs advanced next-generation sequencing technology to identify mutations in the MOGS gene, which plays a critical role in the proper processing of glycoproteins essential for normal cellular function and development.
What Does This Test Measure and Detect?
This comprehensive genetic analysis specifically targets the MOGS (mannosyl-oligosaccharide glucosidase) gene, which encodes an enzyme crucial for the initial steps of N-linked glycosylation. The test detects:
- Pathogenic variants and mutations in the MOGS gene
- Single nucleotide polymorphisms associated with glycosylation disorders
- Insertions, deletions, and copy number variations affecting gene function
- Genetic markers linked to congenital disorders of glycosylation type IIb
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals presenting with:
- Unexplained developmental delays in infancy or childhood
- Neurological symptoms including seizures, hypotonia, or ataxia
- Multisystem involvement affecting liver, gastrointestinal, or endocrine systems
- Family history of congenital disorders of glycosylation
- Abnormal transferrin isoelectric focusing patterns
- Recurrent infections and immune system abnormalities
- Failure to thrive and feeding difficulties in infants
Clinical Benefits of MOGS Gene Testing
Undergoing this genetic analysis provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms or rules out MOGS-related glycosylation disorders with high precision
- Personalized Treatment: Enables targeted therapeutic approaches based on specific genetic findings
- Genetic Counseling: Provides essential information for family planning and recurrence risk assessment
- Early Intervention: Facilitates timely management of symptoms and complications
- Prognostic Information: Helps predict disease progression and potential outcomes
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and metabolic specialists:
- Positive Result: Indicates the presence of pathogenic variants in the MOGS gene, confirming diagnosis of glycosylation disorder type IIb
- Negative Result: Suggests absence of detectable MOGS gene mutations, though other genetic causes should be considered
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Determines if individuals carry one copy of a mutated gene without showing symptoms
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | MOGS Gene Glycosylation Disorder Type 2B NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation of the patient
- Genetic counseling session to create a detailed family pedigree chart
- Discussion of testing implications with a healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic testing facilities ensures accessible, reliable service no matter where you’re located.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about genetic conditions affect your health decisions. Our MOGS Gene Glycosylation Disorder Type 2B NGS Genetic DNA Test provides the definitive answers you need for proper diagnosis and management. With our discounted price of $500 USD, advanced genetic testing is more accessible than ever.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take control of your genetic health with confidence and precision.
