MAPK10 Gene Epileptic Encephalopathy Lennox-Gastaut Type NGS Genetic DNA Test
Comprehensive Genetic Testing for Severe Epilepsy Syndromes
The MAPK10 Gene Epileptic Encephalopathy Lennox-Gastaut Type NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, specifically designed to identify mutations in the MAPK10 gene that are associated with severe childhood-onset epilepsy disorders. This advanced next-generation sequencing test provides critical insights for patients and families affected by treatment-resistant seizure disorders, offering hope for targeted interventions and improved quality of life.
What This Test Measures and Detects
This specialized genetic test utilizes cutting-edge NGS technology to comprehensively analyze the MAPK10 gene for pathogenic variants that cause epileptic encephalopathy and Lennox-Gastaut syndrome. The test specifically identifies:
- Point mutations, deletions, and insertions in the MAPK10 gene
- Variants affecting the mitogen-activated protein kinase signaling pathway
- Genetic alterations that disrupt normal neuronal development and function
- Inherited and de novo mutations associated with severe epilepsy phenotypes
- Specific genetic markers that influence treatment response and prognosis
Who Should Consider This Test
This genetic test is particularly recommended for individuals presenting with the following symptoms and clinical features:
- Children with multiple seizure types including tonic, atonic, and atypical absence seizures
- Patients with treatment-resistant epilepsy that doesn’t respond to standard anti-epileptic drugs
- Individuals showing developmental regression or cognitive decline alongside seizure activity
- Patients with abnormal EEG patterns showing slow spike-and-wave complexes
- Children with early-onset epileptic encephalopathy (before age 8)
- Individuals with a family history of similar neurological disorders
- Patients with unexplained neurological deterioration despite conventional treatments
Key Benefits of MAPK10 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Provides definitive genetic confirmation of MAPK10-related epileptic encephalopathy
- Personalized Treatment: Enables targeted therapeutic approaches based on specific genetic findings
- Prognostic Information: Helps predict disease progression and potential complications
- Family Planning Guidance: Offers crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates timely implementation of appropriate management strategies
- Reduced Diagnostic Odyssey: Minimizes unnecessary testing and medical procedures
- Improved Quality of Life: Supports comprehensive care planning and support services
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and neurologists. The report typically includes:
- Positive Result: Indicates the presence of a pathogenic MAPK10 variant, confirming the genetic basis of the epilepsy syndrome
- Negative Result: Suggests that MAPK10 mutations are not responsible for the clinical presentation, guiding further diagnostic evaluation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires additional research and family studies
- Carrier Status: Provides information about inheritance patterns and recurrence risks for family members
All results are accompanied by detailed explanations and recommendations for next steps in management and family counseling.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and neurological specialists ensures that patients receive comprehensive care and support throughout the testing process.
Pre-Test Requirements
Before scheduling your MAPK10 genetic test, we recommend:
- Comprehensive clinical history documentation of the patient’s neurological symptoms
- Genetic counseling session to create a detailed family pedigree chart
- Review of previous neurological evaluations and test results
- Discussion of testing implications with our genetic specialists
Take Control of Your Neurological Health Today
Don’t let unanswered questions about seizure disorders affect your quality of life. Our MAPK10 Gene Epileptic Encephalopathy Lennox-Gastaut Type NGS Genetic DNA Test provides the clarity and direction needed for effective treatment planning and family management. With our discounted price of $500 USD and comprehensive support services, you can access world-class genetic testing without delay.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our team is ready to help you navigate this important diagnostic journey with compassion and expertise.
