LMNA Gene Limb-Girdle Muscular Dystrophy Autosomal Dominant Type 1B NGS Genetic DNA Test
Comprehensive Genetic Testing for Neurological Disorders
The LMNA Gene Limb-Girdle Muscular Dystrophy Autosomal Dominant Type 1B NGS Genetic DNA Test represents a significant advancement in molecular diagnostics for neuromuscular conditions. This specialized test utilizes state-of-the-art Next-Generation Sequencing technology to analyze the LMNA gene, which encodes lamin A/C proteins essential for nuclear membrane integrity and cellular function.
What This Test Measures and Detects
This comprehensive genetic analysis specifically targets:
- Pathogenic variants in the LMNA gene associated with limb-girdle muscular dystrophy type 1B
- Autosomal dominant inheritance pattern mutations
- Single nucleotide variants, insertions, deletions, and copy number variations
- Genetic markers that differentiate between various muscular dystrophy subtypes
Who Should Consider This Test
This genetic test is recommended for individuals experiencing:
- Progressive muscle weakness in pelvic and shoulder girdle regions
- Difficulty with activities requiring upper body strength
- Walking abnormalities or frequent falls
- Family history of muscular dystrophy or unexplained muscle weakness
- Cardiac conduction abnormalities with muscle symptoms
- Early-onset muscle wasting without clear diagnosis
Clinical Benefits of Genetic Testing
Undergoing this genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out LMNA-related muscular dystrophy
- Proactive Management: Enables early intervention and treatment planning
- Genetic Counseling: Supports informed family planning decisions
- Disease Monitoring: Establishes baseline for disease progression tracking
- Clinical Trial Eligibility: Opens access to targeted therapies and research
Understanding Your Test Results
Our comprehensive genetic report provides:
- Positive Result: Indicates presence of pathogenic LMNA gene variant; consultation with neurologist and genetic counselor recommended
- Negative Result: No disease-causing variants detected in LMNA gene; other diagnostic considerations may be needed
- Variant of Uncertain Significance: Genetic change identified with unclear clinical impact; ongoing monitoring may be advised
- Carrier Status: Information relevant for family members and reproductive planning
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Pre-Test Requirements
Before testing, we recommend:
- Complete clinical history documentation
- Genetic counseling session with our specialists
- Family pedigree chart development
- Neurological examination records
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services with consistent quality standards nationwide.
Take Control of Your Neurological Health
Early genetic diagnosis can significantly impact disease management and quality of life. Our specialized team of neurologists and genetic counselors are available to guide you through the testing process and result interpretation.
Ready to schedule your LMNA Gene Limb-Girdle Muscular Dystrophy Type 1B Genetic Test?
Call our genetic specialists today at +1(267) 388-9828 to book your appointment or discuss testing options. Take the first step toward definitive diagnosis and personalized care management.
