LGI1 Gene Epilepsy Familial Temporal Lobe Type 1 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Familial Temporal Lobe Epilepsy
The LGI1 Gene Epilepsy Familial Temporal Lobe Type 1 NGS Genetic DNA Test represents a breakthrough in neurological genetic testing, specifically designed to identify mutations in the LGI1 (Leucine-rich Glioma Inactivated 1) gene. This sophisticated diagnostic tool utilizes next-generation sequencing technology to provide accurate detection of genetic variations associated with autosomal dominant lateral temporal lobe epilepsy (ADLTE), also known as familial temporal lobe epilepsy type 1.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets the LGI1 gene located on chromosome 10q24, which encodes a secreted neuronal protein crucial for synaptic function and neuronal excitability regulation. The test detects:
- Pathogenic variants and mutations in the LGI1 gene
- Single nucleotide polymorphisms (SNPs) associated with epilepsy risk
- Copy number variations affecting gene function
- Novel genetic alterations impacting protein structure and function
- Inheritance patterns of familial temporal lobe epilepsy
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Unexplained seizures with auditory or sensory symptoms
- Family history of temporal lobe epilepsy across multiple generations
- Seizures beginning in childhood or early adulthood
- Epilepsy symptoms resistant to standard anti-epileptic medications
- Neurological symptoms including déjà vu, jamais vu, or auditory hallucinations
- Patients with suspected genetic epilepsy syndromes
- Individuals planning family with known epilepsy history
Clinical Benefits of LGI1 Genetic Testing
Undergoing LGI1 genetic testing provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out genetic predisposition to familial temporal lobe epilepsy
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates proactive management strategies for at-risk family members
- Prognostic Information: Helps predict disease course and potential complications
- Research Contribution: Advances understanding of genetic epilepsy mechanisms
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert neurologists and genetic counselors:
- Positive Result: Indicates presence of LGI1 gene mutation associated with familial temporal lobe epilepsy
- Negative Result: Suggests absence of tested LGI1 mutations, though other genetic factors may be involved
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical implications requiring further evaluation
- Carrier Status: Determines inheritance patterns and risk to future generations
All results include comprehensive genetic counseling to ensure proper understanding and appropriate next steps for medical management.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | LGI1 Gene Epilepsy Familial Temporal Lobe Type 1 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your LGI1 genetic test, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session with our certified genetic counselors
- Development of detailed family pedigree chart
- Discussion of test implications and potential outcomes
- Informed consent process for genetic testing
Nationwide Testing Availability
We proudly offer the LGI1 Gene Epilepsy Familial Temporal Lobe Type 1 NGS Genetic DNA Test across the United States, with convenient testing locations in:
- New York City, NY
- Los Angeles, CA
- Chicago, IL
- Houston, TX
- Phoenix, AZ
- Philadelphia, PA
- San Antonio, TX
- San Diego, CA
- Dallas, TX
- San Jose, CA
Our network of certified collection centers ensures accessible testing for patients nationwide.
Take Control of Your Neurological Health Today
Don’t let uncertainty about genetic epilepsy risk impact your quality of life. Our comprehensive LGI1 genetic testing provides the clarity and information needed for informed healthcare decisions. With advanced NGS technology and expert neurological interpretation, you can trust our testing for accurate, reliable results.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic epilepsy risk and securing your neurological future.
