KRT14 Gene Epidermolysis Bullosa Simplex Koebner Type NGS Genetic DNA Test
Comprehensive Genetic Testing for Inherited Skin Disorders
The KRT14 Gene Epidermolysis Bullosa Simplex Koebner Type NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for inherited skin conditions. This advanced test specifically targets mutations in the KRT14 gene, which plays a critical role in maintaining skin integrity and structural stability. Epidermolysis Bullosa Simplex, Koebner type is a genetic disorder characterized by skin fragility where minor friction or trauma causes painful blistering and skin separation.
What This Test Measures and Detects
Our NGS-based genetic test provides comprehensive analysis of the KRT14 gene to identify pathogenic variants responsible for Epidermolysis Bullosa Simplex, Koebner type. The test examines:
- Complete sequencing of the KRT14 gene coding regions
- Detection of point mutations, insertions, and deletions
- Identification of genetic variants affecting keratin 14 protein structure
- Assessment of mutation impact on epidermal basal cell integrity
Who Should Consider This Genetic Test
This test is recommended for individuals experiencing:
- Unexplained skin blistering from minimal friction or trauma
- Family history of Epidermolysis Bullosa or similar skin fragility disorders
- Recurrent skin erosions and healing difficulties
- Nail dystrophy or abnormalities
- Oral mucosal blistering with eating or dental care
- Planning pregnancy with known family history of skin genetic disorders
Clinical Benefits of Genetic Testing
Undergoing the KRT14 genetic test provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out genetic cause of symptoms
- Personalized Treatment: Guides appropriate wound care and management strategies
- Genetic Counseling: Informs family planning decisions and recurrence risks
- Early Intervention: Enables proactive management to prevent complications
- Differential Diagnosis: Distinguishes from other blistering skin conditions
Understanding Your Test Results
Your genetic test results will be thoroughly explained during your genetic counseling session. Possible outcomes include:
- Positive Result: Identifies a pathogenic mutation in KRT14 gene confirming diagnosis
- Negative Result: No disease-causing variants detected in KRT14 gene
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Identifies individuals who carry one copy of mutated gene
Test Details and Pricing
| Test Feature | Details |
|---|---|
| Test Name | KRT14 Gene Epidermolysis Bullosa Simplex Koebner Type NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures accessible genetic testing services for patients nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about your genetic health prevent you from getting the answers you need. Our specialized genetic testing provides the clarity required for informed healthcare decisions and personalized treatment approaches.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your KRT14 genetic test consultation and take control of your genetic health journey.
