KLK4 Gene Amelogenesis Imperfecta Type 2A1 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Dental Disorders
The KLK4 Gene Amelogenesis Imperfecta Type 2A1 NGS Genetic DNA Test represents a breakthrough in genetic dentistry, offering precise identification of mutations responsible for Amelogenesis Imperfecta type 2A1. This hereditary condition affects enamel formation, leading to significant dental complications that impact both oral health and quality of life.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets the KLK4 (Kallikrein-Related Peptidase 4) gene, which plays a crucial role in enamel matrix degradation during tooth development. The test utilizes Next-Generation Sequencing technology to:
- Identify pathogenic variants in the KLK4 gene
- Detect single nucleotide polymorphisms associated with enamel defects
- Analyze gene mutations causing autosomal recessive Amelogenesis Imperfecta
- Provide comprehensive genetic profiling for hereditary dental conditions
Who Should Consider This Genetic Test?
This test is recommended for individuals displaying symptoms of enamel formation disorders, including:
- Children and adults with unusually thin or absent enamel
- Individuals experiencing severe tooth discoloration (yellow-brown teeth)
- Patients with increased tooth sensitivity to temperature changes
- Those showing rapid tooth wear and enamel erosion
- Individuals with recurrent dental caries despite good oral hygiene
- Patients with family history of similar dental conditions
- Children showing delayed or abnormal tooth eruption patterns
Key Benefits of KLK4 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Provides definitive genetic confirmation of Amelogenesis Imperfecta type 2A1
- Personalized Treatment Planning: Enables customized dental care strategies based on genetic findings
- Early Intervention: Facilitates proactive dental management before severe complications develop
- Family Planning Guidance: Offers valuable information for genetic counseling and reproductive decisions
- Comprehensive Understanding: Helps patients and families understand the hereditary nature of their condition
- Improved Quality of Life: Supports better long-term dental health outcomes through targeted interventions
Understanding Your Test Results
Your genetic test results will provide clear insights into your KLK4 gene status:
- Positive Result: Indicates the presence of pathogenic mutations in the KLK4 gene, confirming Amelogenesis Imperfecta type 2A1 diagnosis
- Negative Result: Suggests no detectable mutations in the KLK4 gene, though other genetic or environmental factors may still be involved
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Determines if you carry one copy of the mutated gene, important for family planning considerations
Our genetic counselors will provide comprehensive interpretation of your results and guide you through next steps for dental management and family planning.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| KLK4 Gene Amelogenesis Imperfecta Type 2A1 NGS Genetic DNA Test – Discount Price | $500 |
| KLK4 Gene Amelogenesis Imperfecta Type 2A1 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic testing facilities ensures accessible, reliable testing nationwide.
Take Control of Your Dental Health Today
Don’t let hereditary dental conditions compromise your oral health and quality of life. Our KLK4 Gene Amelogenesis Imperfecta Type 2A1 NGS Genetic DNA Test provides the genetic insights needed for effective dental management and informed healthcare decisions.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic dental health.
Our team of genetic specialists and dental professionals is ready to provide comprehensive support throughout your testing journey, from initial consultation to result interpretation and ongoing care planning.
