IGF1R Gene Insulin-like Growth Factor Resistance NGS Genetic DNA Test
Comprehensive Genetic Analysis for Growth Hormone Resistance
The IGF1R Gene Insulin-like Growth Factor Resistance NGS Genetic DNA Test represents a cutting-edge diagnostic approach to understanding genetic factors affecting growth hormone sensitivity and metabolic function. This sophisticated test utilizes next-generation sequencing technology to comprehensively analyze the IGF1R gene, which encodes the insulin-like growth factor 1 receptor – a critical component in the growth hormone signaling pathway.
What Does This Test Measure?
This advanced genetic test specifically targets and sequences the entire IGF1R gene to identify:
- Point mutations affecting receptor function
- Insertions or deletions disrupting gene structure
- Copy number variations impacting gene dosage
- Regulatory region mutations affecting gene expression
- Novel genetic variants with potential clinical significance
Who Should Consider This Test?
This genetic analysis is particularly recommended for individuals experiencing:
- Unexplained growth retardation or short stature
- Family history of growth hormone resistance
- Developmental delays with unknown etiology
- Metabolic abnormalities despite normal growth hormone levels
- Clinical features suggestive of IGF-1 resistance syndrome
- Children with disproportionate growth patterns
- Individuals with suspected genetic metabolic disorders
Clinical Benefits and Applications
Undergoing the IGF1R Gene Resistance Test provides numerous clinical advantages:
- Accurate diagnosis of genetic causes for growth abnormalities
- Personalized treatment planning based on genetic findings
- Family genetic counseling and risk assessment
- Early intervention opportunities for affected children
- Clarification of ambiguous clinical presentations
- Guidance for appropriate growth hormone therapy
- Improved understanding of metabolic implications
Understanding Your Test Results
Your comprehensive genetic report will include detailed interpretation of findings:
- Positive Result: Identifies specific IGF1R gene mutations associated with insulin-like growth factor resistance, providing clear diagnostic information for clinical management.
- Negative Result: No pathogenic variants detected in the IGF1R gene, suggesting alternative causes for clinical symptoms should be investigated.
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical impact, requiring correlation with clinical findings and possible family studies.
- Carrier Status: May identify individuals carrying recessive mutations who could pass genetic risk to offspring.
Test Specifications and Pricing
| Test Component | Details |
|---|---|
| Test Name | IGF1R Gene Insulin-like Growth Factor Resistance NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
To ensure optimal testing outcomes, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session with certified genetic counselor
- Development of detailed family pedigree chart
- Discussion of potential implications and limitations
- Informed consent process completion
Nationwide Accessibility
General Genetics Corporation maintains testing facilities across the United States, with convenient locations in:
- New York City and surrounding metropolitan areas
- Los Angeles and Southern California regions
- Chicago and Midwest territories
- Houston and Texas medical centers
- Phoenix and Southwest facilities
- All major metropolitan areas nationwide
Take Control of Your Genetic Health
Understanding your genetic predispositions to metabolic disorders and growth abnormalities can significantly impact your healthcare journey. The IGF1R Gene Resistance Test provides crucial insights that can guide medical decisions and family planning. Our team of genetic specialists and certified counselors are available to support you throughout the testing process and result interpretation.
Ready to gain clarity about your genetic health? Book your IGF1R Gene Insulin-like Growth Factor Resistance NGS Genetic DNA Test today by calling our dedicated genetic counseling team at +1(267) 388-9828 or schedule your appointment online through our secure patient portal.
