GRID2 Gene Spinocerebellar Ataxia Type 18 Autosomal Recessive NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Neurological Disorders
The GRID2 Gene Spinocerebellar Ataxia Type 18 Autosomal Recessive NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying mutations responsible for this rare inherited neurological condition. Spinocerebellar ataxia type 18 is characterized by progressive degeneration of the cerebellum and spinal cord, leading to significant motor coordination challenges. This test provides definitive genetic confirmation, enabling accurate diagnosis and informed medical management decisions.
What This Advanced Genetic Test Detects
Our specialized NGS-based examination precisely identifies pathogenic variants in the GRID2 gene, which encodes the glutamate receptor delta-2 subunit. This protein plays a critical role in cerebellar synaptic function and neuronal communication. The test comprehensively analyzes:
- Point mutations and small insertions/deletions in the GRID2 gene
- Autosomal recessive inheritance pattern confirmation
- Novel genetic variants associated with cerebellar ataxia
- Carrier status identification for family planning purposes
Who Should Consider GRID2 Genetic Testing?
This specialized genetic test is recommended for individuals presenting with symptoms suggestive of spinocerebellar ataxia or those with family history of neurological disorders. Key indications include:
Clinical Symptoms Warranting Testing
- Progressive gait instability and coordination difficulties
- Speech abnormalities including slurred or scanning speech
- Involuntary eye movements (nystagmus)
- Muscle stiffness and spasticity
- Difficulty with fine motor tasks and handwriting
- Balance problems and frequent falls
- Family history of similar neurological symptoms
Genetic Counseling Considerations
Individuals with known family history of spinocerebellar ataxia or consanguineous relationships should strongly consider genetic counseling before testing. Our comprehensive pre-test genetic counseling session includes detailed pedigree analysis to assess inheritance patterns and recurrence risks.
Significant Benefits of GRID2 Genetic Testing
Undergoing this advanced genetic examination provides numerous advantages for patients and healthcare providers:
Diagnostic Clarity and Treatment Planning
- Definitive diagnosis eliminating diagnostic uncertainty
- Personalized treatment strategies based on genetic findings
- Accurate prognosis assessment and disease progression monitoring
- Eligibility determination for clinical trials and emerging therapies
Family Planning and Genetic Counseling
- Carrier status identification for at-risk family members
- Informed reproductive decision-making
- Prenatal testing options for future pregnancies
- Comprehensive genetic risk assessment for extended family
Understanding Your Test Results
Our expert genetic counselors provide detailed interpretation of your GRID2 gene analysis results:
Positive Result Interpretation
A positive result indicates the presence of pathogenic mutations in both copies of the GRID2 gene, confirming spinocerebellar ataxia type 18 diagnosis. This finding enables targeted management strategies and family screening recommendations.
Negative Result Significance
A negative result suggests that GRID2 gene mutations were not detected, though other genetic or non-genetic causes of ataxia should still be considered. Further neurological evaluation may be recommended.
Variant of Uncertain Significance
Some genetic changes may be classified as variants of uncertain significance, requiring additional family studies and periodic re-evaluation as scientific knowledge advances.
Test Specifications and Pricing
| Test Component | Details |
|---|---|
| Test Name | GRID2 Gene Spinocerebellar Ataxia Type 18 Autosomal Recessive NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Medical Specialty | Neurology and Genetics |
Nationwide Accessibility and Convenient Testing
We maintain comprehensive testing facilities across the United States, with specialized collection centers in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and numerous other cities. Our network ensures convenient access to advanced genetic testing regardless of your location.
Pre-Test Requirements
Before scheduling your GRID2 genetic test, please ensure you have:
- Complete clinical history documentation
- Referral from your neurologist or genetic specialist
- Completed genetic counseling session with pedigree analysis
- Insurance pre-authorization if applicable
Take Control of Your Neurological Health Today
Don’t let uncertainty about hereditary neurological conditions affect your quality of life. Our GRID2 Gene Spinocerebellar Ataxia Type 18 testing provides the clarity needed for informed healthcare decisions and family planning. With our discounted rate of $500 USD, advanced genetic testing is more accessible than ever.
Schedule your comprehensive genetic evaluation today by calling our dedicated genetic counseling team at +1(267) 388-9828 or book your appointment online through our secure patient portal.
Our expert genetic counselors and neurological specialists are committed to providing compassionate care and comprehensive support throughout your diagnostic journey. Take the first step toward definitive answers and personalized medical management.
