GABRG2 Gene Generalized Epilepsy with Febrile Seizures Plus Type 3 NGS Genetic DNA Test
Understanding GABRG2 Gene Epilepsy Testing
The GABRG2 Gene Generalized Epilepsy with Febrile Seizures Plus Type 3 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics. This advanced test specifically examines the GABRG2 gene, which encodes the gamma-aminobutyric acid type A receptor subunit gamma-2. This receptor plays a critical role in inhibitory neurotransmission within the central nervous system, making it essential for proper brain function and seizure regulation.
What This Test Measures and Detects
Our comprehensive NGS-based analysis targets the GABRG2 gene to identify pathogenic variants associated with:
- Generalized epilepsy with febrile seizures plus (GEFS+) type 3
- Various mutation types including missense, nonsense, and frameshift variants
- Genetic alterations affecting GABA receptor function
- Inherited patterns of seizure susceptibility
- Specific genetic markers for treatment response prediction
Who Should Consider GABRG2 Genetic Testing?
This specialized genetic test is particularly recommended for individuals experiencing:
- Febrile seizures that persist beyond age 6
- Multiple seizure types including absence, myoclonic, or tonic-clonic seizures
- Family history of epilepsy or febrile seizures
- Unexplained childhood-onset seizure disorders
- Resistance to conventional anti-epileptic medications
- Developmental delays associated with seizure activity
Clinical Benefits of GABRG2 Testing
Undergoing GABRG2 genetic analysis provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms specific genetic etiology of seizure disorders
- Personalized Treatment: Guides selection of appropriate anti-epileptic drugs
- Family Planning: Provides crucial information for genetic counseling
- Prognostic Information: Helps predict disease course and potential complications
- Early Intervention: Enables proactive management strategies
- Reduced Diagnostic Uncertainty: Eliminates years of diagnostic odyssey
Understanding Your Test Results
Our comprehensive genetic report includes detailed interpretation of your GABRG2 gene analysis:
- Positive Result: Indicates presence of a pathogenic variant associated with increased seizure risk
- Negative Result: Suggests absence of tested GABRG2 mutations but doesn’t rule out other genetic causes
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Important for family members and reproductive planning
All results are accompanied by genetic counseling recommendations and clinical management guidance from our expert neurologists and genetic specialists.
Test Specifications and Pricing
| Test Feature | Details |
|---|---|
| Test Name | GABRG2 Gene Generalized Epilepsy with Febrile Seizures Plus Type 3 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Preparation Requirements
To ensure optimal testing outcomes, we recommend:
- Complete clinical history documentation of the patient
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Informed consent process for genetic testing
- Review of insurance coverage and potential out-of-pocket costs
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified collection centers ensures easy access to this vital genetic testing service.
Take Control of Your Neurological Health Today
Don’t let uncertainty about your seizure disorder continue. Our GABRG2 genetic test provides the clarity needed for effective treatment planning and family risk assessment. With advanced NGS technology and expert interpretation, you’ll receive comprehensive insights into your genetic predisposition to epilepsy syndromes.
Ready to begin your genetic testing journey? Contact our genetic specialists today at +1(267) 388-9828 or schedule your appointment online. Take the first step toward personalized neurological care and evidence-based treatment decisions.
