FASLG Gene Autoimmune Lymphoproliferative Syndrome Type 1B NGS Genetic DNA Test
Comprehensive Genetic Testing for Autoimmune Lymphoproliferative Disorders
The FASLG Gene Autoimmune Lymphoproliferative Syndrome Type 1B NGS Genetic DNA Test represents a breakthrough in precision medicine for diagnosing rare autoimmune conditions. This advanced genetic test specifically targets mutations in the FASLG gene, which plays a critical role in regulating programmed cell death (apoptosis) within the immune system. When this gene malfunctions, it can lead to Autoimmune Lymphoproliferative Syndrome Type 1B (ALPS1B), a condition characterized by abnormal lymphocyte accumulation and autoimmune manifestations.
What This Test Measures and Detects
Our state-of-the-art NGS (Next-Generation Sequencing) technology provides comprehensive analysis of the FASLG gene to identify:
- Pathogenic mutations in the FASLG gene coding regions
- Single nucleotide variants (SNVs) affecting protein function
- Insertions and deletions that disrupt normal gene expression
- Genetic variations associated with impaired apoptosis signaling
- Inheritance patterns for family genetic counseling
The test examines the entire coding sequence of the FASLG gene, ensuring no potential mutation goes undetected. This comprehensive approach provides clinicians with definitive genetic evidence to confirm or rule out ALPS1B diagnosis.
Who Should Consider This Test
This genetic test is recommended for individuals presenting with the following symptoms or clinical indications:
- Unexplained chronic lymphadenopathy (swollen lymph nodes)
- Persistent splenomegaly (enlarged spleen) without clear cause
- Autoimmune manifestations affecting multiple organ systems
- Recurrent autoimmune cytopenias (low blood cell counts)
- Family history of autoimmune lymphoproliferative disorders
- Unexplained hepatomegaly (enlarged liver)
- Chronic non-malignant lymphoproliferation
- Increased double-negative T-cells in peripheral blood
- Elevated serum vitamin B12 levels
- Hypergammaglobulinemia
Clinical Benefits of FASLG Genetic Testing
Undergoing FASLG gene testing provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out ALPS1B with genetic certainty
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning: Provides crucial information for genetic counseling and family planning decisions
- Prognostic Information: Helps predict disease progression and potential complications
- Therapeutic Guidance: Informs treatment selection, including immunosuppressive therapies
- Risk Assessment: Identifies at-risk family members for early intervention
- Differential Diagnosis: Distinguishes ALPS1B from other autoimmune and lymphoproliferative disorders
Understanding Your Test Results
Your FASLG gene test results will be carefully interpreted by our team of certified genetic counselors and medical geneticists:
- Positive Result: Indicates the presence of a pathogenic FASLG mutation confirming ALPS1B diagnosis. This result enables targeted management and family screening.
- Negative Result: Suggests that FASLG mutations are not the cause of symptoms, guiding investigation toward other potential diagnoses.
- Variant of Uncertain Significance (VUS): Identifies a genetic change with unclear clinical implications, requiring further evaluation and possibly family studies.
- Carrier Status: For family members, identifies individuals who carry the mutation but may not show symptoms.
All results include comprehensive interpretation and recommendations for next steps in clinical management. Our genetic counseling team is available to discuss results and provide guidance for patients and families.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have conveniently located branches across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art facilities ensure consistent, high-quality testing regardless of location.
Take Control of Your Health Today
Don’t let unexplained autoimmune symptoms or family history of lymphoproliferative disorders go undiagnosed. The FASLG Gene Autoimmune Lymphoproliferative Syndrome Type 1B NGS Genetic DNA Test provides the definitive answers you need for proper diagnosis and treatment planning.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment. Our compassionate team is ready to answer your questions, explain the testing process, and help you take the next step toward better health.
Early diagnosis through genetic testing can significantly improve treatment outcomes and quality of life for individuals with autoimmune lymphoproliferative syndromes. Take advantage of our special discounted pricing and book your test today!
