ESRRB Gene Deafness Autosomal Recessive Type 35 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Hearing Loss
The ESRRB Gene Deafness Autosomal Recessive Type 35 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing disorders. This advanced test specifically targets mutations in the ESRRB (Estrogen Related Receptor Beta) gene, which plays a crucial role in the development and function of the inner ear. Autosomal recessive type 35 deafness is a significant cause of congenital or early-onset hearing loss, making early detection through genetic testing essential for proper management and intervention strategies.
What Does This Test Measure and Detect?
This comprehensive genetic analysis utilizes Next-Generation Sequencing (NGS) technology to examine the entire coding region of the ESRRB gene for pathogenic variants. The test specifically identifies:
- Point mutations, deletions, and insertions in the ESRRB gene
- Autosomal recessive inheritance patterns associated with hearing loss
- Specific genetic markers linked to nonsyndromic hearing impairment
- Variants that affect inner ear development and auditory function
- Genetic risk factors for congenital or progressive hearing loss
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing the following symptoms or circumstances:
- Children with unexplained congenital or early-onset hearing loss
- Individuals with family history of hereditary deafness
- Couples planning pregnancy with known genetic risk factors for hearing disorders
- Patients with progressive hearing loss without clear environmental causes
- Individuals from populations with higher prevalence of autosomal recessive hearing conditions
- Patients undergoing evaluation for cochlear implant candidacy
- Those with siblings or relatives diagnosed with ESRRB-related hearing disorders
Key Benefits of ESRRB Genetic Testing
Undergoing this advanced genetic test provides numerous advantages for patients and healthcare providers:
- Early Intervention Opportunities: Early genetic diagnosis enables timely implementation of hearing aids, cochlear implants, or communication therapies
- Accurate Diagnosis: Provides definitive genetic confirmation when environmental causes have been ruled out
- Family Planning Guidance: Helps couples understand genetic risks for future children
- Personalized Treatment Plans: Enables ENT specialists to develop targeted management strategies
- Reduced Diagnostic Uncertainty: Eliminates prolonged diagnostic odysseys and unnecessary testing
- Genetic Counseling Support: Provides basis for comprehensive genetic counseling and family education
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and medical geneticists. The report typically includes:
- Positive Result: Indicates the presence of pathogenic ESRRB gene mutations, confirming genetic diagnosis of autosomal recessive deafness type 35
- Negative Result: Suggests that no known pathogenic variants were detected in the ESRRB gene
- Variant of Uncertain Significance (VUS): Identifies genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Determines if an individual carries one copy of a mutated gene without showing symptoms
All positive results are accompanied by detailed genetic counseling to help you understand the implications for your health and family planning decisions.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We have conveniently located branches across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art genetic testing facilities ensure consistent, high-quality results regardless of your location.
Pre-Test Preparation and Requirements
Before scheduling your test, we recommend:
- Providing complete clinical history related to hearing concerns
- Participating in a genetic counseling session to discuss family history
- Completing a pedigree chart documenting family members with hearing disorders
- Consulting with your ENT specialist about the appropriateness of genetic testing
Take Control of Your Hearing Health Today
Don’t let uncertainty about hereditary hearing conditions affect your quality of life. Our ESRRB Gene Deafness Autosomal Recessive Type 35 NGS Genetic DNA Test provides the clarity you need to make informed healthcare decisions. With results available in just 3-4 weeks and multiple sample collection options (blood, extracted DNA, or one drop of blood on FTA card), getting tested has never been more convenient.
Ready to schedule your genetic test? Call or WhatsApp us today at +1(267) 388-9828 to book your appointment or speak with our genetic counseling team. Take the first step toward understanding your genetic hearing health with confidence and precision.
