ENAM Gene Amelogenesis Imperfecta Type 1B NGS Genetic DNA Test
Comprehensive Genetic Analysis for Enamel Development Disorders
The ENAM Gene Amelogenesis Imperfecta Type 1B NGS Genetic DNA Test represents a cutting-edge diagnostic tool in the field of genetic dentistry and dermatology. This advanced genetic test specifically targets mutations in the ENAM (Enamelin) gene, which plays a critical role in proper enamel formation during tooth development. Amelogenesis Imperfecta type 1B is a hereditary condition characterized by defective enamel structure, leading to various dental complications throughout an individual’s lifetime.
What Does This Test Measure and Detect?
This comprehensive genetic test utilizes Next-Generation Sequencing (NGS) technology to analyze the entire coding region of the ENAM gene. The test specifically detects:
- Point mutations and single nucleotide variants in the ENAM gene
- Small insertions and deletions affecting enamelin protein production
- Genetic variations associated with autosomal dominant Amelogenesis Imperfecta
- Mutations that disrupt normal enamel matrix formation and mineralization
- Genetic markers linked to enamel hypoplasia and structural defects
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals exhibiting the following symptoms or clinical presentations:
- Children or adults with unusually thin, pitted, or grooved tooth enamel
- Individuals experiencing rapid tooth wear or enamel erosion
- Patients with yellow, brown, or gray tooth discoloration not related to hygiene
- Families with a history of inherited dental enamel defects
- Individuals experiencing tooth sensitivity due to enamel abnormalities
- Patients with multiple dental restorations at a young age
- Those with suspected genetic enamel disorders despite good oral hygiene
Significant Benefits of Genetic Testing
Undergoing the ENAM Gene Amelogenesis Imperfecta Type 1B test provides numerous advantages:
- Accurate Diagnosis: Confirms the genetic basis of enamel defects, eliminating diagnostic uncertainty
- Personalized Treatment Planning: Enables dentists to develop targeted treatment strategies based on genetic findings
- Family Planning Guidance: Provides crucial information for genetic counseling and family planning decisions
- Early Intervention: Allows for proactive dental care management from childhood
- Comprehensive Understanding: Helps patients and families understand the hereditary nature of their condition
- Psychological Relief: Reduces anxiety by providing definitive answers about dental health concerns
Understanding Your Test Results
After completing the ENAM Gene Amelogenesis Imperfecta Type 1B NGS Genetic DNA Test, you will receive a comprehensive report that includes:
- Positive Result: Indicates the presence of a pathogenic mutation in the ENAM gene, confirming the diagnosis of Amelogenesis Imperfecta type 1B. This result provides definitive genetic evidence for the enamel disorder.
- Negative Result: Suggests no disease-causing mutations were detected in the ENAM gene. However, this does not completely rule out other genetic causes of enamel defects.
- Variant of Uncertain Significance (VUS): Identifies genetic changes whose clinical significance is currently unknown. Additional family studies may be recommended.
All results are accompanied by detailed interpretation and recommendations for follow-up care. Genetic counseling is strongly recommended to fully understand the implications of your test results and discuss appropriate management strategies.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | ENAM Gene Amelogenesis Imperfecta Type 1B NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your ENAM Gene Amelogenesis Imperfecta Type 1B test, please ensure:
- Complete clinical history of the patient undergoing testing
- Genetic counseling session to create a detailed family pedigree chart
- Documentation of affected family members with similar dental conditions
- Current dental examination records and photographs if available
Nationwide Testing Availability
We proudly offer the ENAM Gene Amelogenesis Imperfecta Type 1B NGS Genetic DNA Test across the United States through our extensive network of testing facilities. Our services are available in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities nationwide.
Take Control of Your Dental Health Today
Don’t let uncertainty about your dental health or family genetic history continue. The ENAM Gene Amelogenesis Imperfecta Type 1B NGS Genetic DNA Test provides the clarity and answers you need to make informed decisions about your dental care and family planning. Our experienced genetic counselors and dental specialists are ready to guide you through the testing process and help you understand your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic dental health.
Early diagnosis through genetic testing can significantly improve long-term dental outcomes and quality of life. Book your appointment now and benefit from our specialized expertise in genetic enamel disorders.
