DPYD Gene Dihydropyrimidine Dehydrogenase Deficiency NGS Genetic DNA Test
Comprehensive Genetic Screening for Safe Medication Management
The DPYD Gene Dihydropyrimidine Dehydrogenase Deficiency NGS Genetic DNA Test represents a breakthrough in personalized medicine, offering crucial insights into how your body metabolizes specific medications. This advanced genetic screening identifies mutations in the DPYD gene that can significantly impact treatment outcomes, particularly for patients undergoing cancer therapy with fluoropyrimidine drugs.
What This Test Measures and Detects
Our comprehensive NGS-based test analyzes the complete DPYD gene sequence to identify:
- Genetic variants associated with dihydropyrimidine dehydrogenase deficiency
- Mutations affecting enzyme activity levels
- Specific polymorphisms that influence drug metabolism
- Risk factors for severe toxicity during chemotherapy
- Inherited metabolic disorder patterns
Who Should Consider This Genetic Test
This test is particularly important for individuals who:
- Are scheduled to receive fluoropyrimidine-based chemotherapy (5-FU, capecitabine)
- Have a family history of metabolic disorders or adverse drug reactions
- Experience unexplained neurological symptoms or developmental delays
- Have relatives diagnosed with dihydropyrimidine dehydrogenase deficiency
- Are planning cancer treatment and want personalized medication dosing
- Show symptoms of pyrimidine metabolism disorders
Key Benefits of DPYD Genetic Testing
- Personalized Cancer Treatment: Enables tailored chemotherapy dosing to maximize effectiveness while minimizing toxicity
- Risk Prevention: Identifies patients at high risk for severe adverse drug reactions before treatment begins
- Family Planning: Provides genetic information for family members who may be at risk
- Early Intervention: Allows for proactive management of potential metabolic complications
- Treatment Optimization: Helps oncologists design safer, more effective treatment protocols
Understanding Your Test Results
Your genetic test results will fall into one of several categories:
- Normal/Negative: No significant DPYD mutations detected, indicating normal enzyme function
- Carrier Status: One copy of a mutated gene, typically with reduced enzyme activity
- Deficient/Positive: Two mutated copies indicating complete enzyme deficiency
- Intermediate Activity: Partial enzyme deficiency requiring dose adjustments
Our genetic counselors will provide detailed interpretation and guidance based on your specific results, helping you and your healthcare provider make informed treatment decisions.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | DPYD Gene Dihydropyrimidine Dehydrogenase Deficiency NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures that quality genetic testing is accessible to patients nationwide.
Take Control of Your Treatment Journey
Don’t leave your medication safety to chance. The DPYD genetic test provides essential information that can significantly impact your treatment outcomes and quality of life. Our experienced genetic counselors and medical professionals are ready to guide you through the testing process and help interpret your results.
Ready to schedule your genetic screening? Call our dedicated healthcare line at +1(267) 388-9828 or book your appointment online today. Take the first step toward personalized, safer medical treatment with our comprehensive DPYD genetic analysis.
