DNAI1 Gene Primary Ciliary Dyskinesia Type 1 NGS Genetic DNA Test
Comprehensive Genetic Testing for Ciliary Disorders
The DNAI1 Gene Primary Ciliary Dyskinesia Type 1 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with Primary Ciliary Dyskinesia (PCD). This specialized test focuses on the DNAI1 gene, which plays a crucial role in the proper formation and function of motile cilia throughout the body. Cilia are microscopic, hair-like structures that line the respiratory tract, reproductive system, and other vital organs, serving essential functions in mucus clearance, fluid movement, and cellular signaling.
What Does This Test Measure?
This advanced genetic test specifically targets and analyzes the DNAI1 gene using Next-Generation Sequencing (NGS) technology to detect:
- Pathogenic mutations in the DNAI1 gene sequence
- Single nucleotide variants (SNVs) affecting ciliary protein structure
- Insertions and deletions that disrupt normal gene function
- Copy number variations impacting gene dosage
- Splice site mutations affecting protein production
Who Should Consider This Test?
This genetic test is particularly recommended for individuals presenting with:
- Chronic respiratory symptoms beginning in infancy or early childhood
- Recurrent pneumonia and bronchitis despite adequate treatment
- Persistent nasal congestion and sinusitis requiring frequent medical intervention
- Chronic middle ear infections with associated hearing difficulties
- Bronchiectasis confirmed through imaging studies
- Situs inversus (organs positioned on opposite sides of the body)
- Family history of Primary Ciliary Dyskinesia or related ciliary disorders
- Infertility issues in males due to impaired sperm motility
Clinical Benefits of DNAI1 Genetic Testing
Undergoing DNAI1 gene testing provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out Primary Ciliary Dyskinesia Type 1 with high precision
- Early Intervention: Enables proactive management strategies before significant lung damage occurs
- Personalized Treatment: Guides targeted therapies based on specific genetic findings
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Prognostic Information: Helps predict disease progression and potential complications
- Reduced Diagnostic Odyssey: Minimizes unnecessary testing and medical procedures
Understanding Your Test Results
Your DNAI1 gene test results will fall into one of several categories:
- Positive Result: Identifies pathogenic mutations confirming Primary Ciliary Dyskinesia Type 1 diagnosis
- Negative Result: No disease-causing mutations detected in the DNAI1 gene
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Identifies individuals with one mutated copy who may pass the condition to offspring
All results are accompanied by comprehensive interpretation from our board-certified genetic specialists, ensuring you receive clear, actionable information about your genetic health status.
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| DNAI1 Gene Primary Ciliary Dyskinesia Type 1 NGS Genetic DNA Test – Discount Price | $500 |
| DNAI1 Gene Primary Ciliary Dyskinesia Type 1 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas. Our state-of-the-art facilities in New York, Los Angeles, Chicago, Houston, Phoenix, and other key cities ensure accessible, high-quality genetic testing for patients nationwide.
Take Control of Your Respiratory Health
Don’t let unexplained respiratory symptoms compromise your quality of life. The DNAI1 Gene Primary Ciliary Dyskinesia Type 1 NGS Genetic DNA Test provides the clarity needed for proper diagnosis and effective management of ciliary disorders. Our experienced genetic counselors and ENT specialists are ready to guide you through the testing process and help interpret your results.
Ready to schedule your genetic test? Contact our dedicated patient care team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic health and developing an effective treatment strategy tailored to your specific needs.
