DNAH9 Gene Primary Ciliary Dyskinesia NGS Genetic DNA Test
Comprehensive Genetic Testing for Ciliary Disorders
The DNAH9 Gene Primary Ciliary Dyskinesia NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations responsible for primary ciliary dyskinesia (PCD). This specialized genetic test utilizes next-generation sequencing technology to analyze the DNAH9 gene, which plays a critical role in the proper functioning of cilia – the microscopic, hair-like structures that line the respiratory tract and other organs.
What is Primary Ciliary Dyskinesia?
Primary ciliary dyskinesia is a rare genetic disorder characterized by impaired ciliary function throughout the body. Cilia are essential for moving mucus, debris, and pathogens out of the respiratory system, and they also play crucial roles in reproductive health and organ placement during embryonic development. When cilia don’t function properly, individuals experience recurrent respiratory infections, chronic sinusitis, and other related health complications.
What the Test Measures and Detects
This advanced genetic test specifically targets the DNAH9 gene using next-generation sequencing technology to identify:
- Pathogenic variants and mutations in the DNAH9 gene
- Single nucleotide polymorphisms (SNPs) associated with ciliary dysfunction
- Deletions, insertions, and other structural variations
- Inheritance patterns of DNAH9-related disorders
- Genetic markers for primary ciliary dyskinesia susceptibility
Technical Specifications
- Methodology: Next-Generation Sequencing (NGS) Technology
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Turnaround Time: 3 to 4 Weeks
- Specialty: ENT Doctor
- Department: Genetics
Who Should Consider This Test
This genetic test is recommended for individuals experiencing symptoms suggestive of primary ciliary dyskinesia or those with a family history of ciliary disorders:
Clinical Indications and Symptoms
- Chronic respiratory infections beginning in infancy or childhood
- Persistent nasal congestion and sinusitis
- Recurrent middle ear infections and hearing loss
- Chronic cough with productive sputum
- Bronchiectasis (damaged airways)
- Infertility or subfertility in males due to immotile sperm
- Heterotaxy (abnormal organ positioning)
- Family history of primary ciliary dyskinesia
- Neonatal respiratory distress without clear cause
Benefits of DNAH9 Genetic Testing
Undergoing the DNAH9 Gene Primary Ciliary Dyskinesia test provides numerous clinical advantages:
Diagnostic Clarity
- Provides definitive diagnosis for individuals with suspected PCD
- Differentiates between various forms of ciliary disorders
- Helps avoid unnecessary treatments and procedures
- Enables targeted management strategies
Personalized Treatment Planning
- Guides appropriate respiratory therapy interventions
- Informs fertility counseling and reproductive planning
- Helps anticipate and prevent complications
- Supports individualized monitoring protocols
Family Genetic Counseling
- Identifies inheritance patterns within families
- Provides recurrence risk information for future pregnancies
- Enables early intervention for affected family members
- Supports informed reproductive decisions
Understanding Your Test Results
Your DNAH9 genetic test results will be carefully interpreted by our team of genetic specialists and ENT doctors:
Possible Result Interpretations
- Positive Result: Identifies pathogenic variants in the DNAH9 gene confirming primary ciliary dyskinesia diagnosis
- Negative Result: No disease-causing variants detected in the DNAH9 gene
- Variant of Uncertain Significance (VUS): Identifies genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Identifies individuals who carry one copy of a mutated gene but don’t show symptoms
Post-Test Guidance
All positive results include comprehensive genetic counseling to help you understand the implications for your health and family planning. Our specialists will provide personalized recommendations for management, monitoring, and family testing when appropriate.
Test Pricing and Booking Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 USD |
| Regular Price | $700 USD |
Nationwide Availability
We have branches across the United States, making genetic testing accessible in major cities including:
- New York, NY
- Los Angeles, CA
- Chicago, IL
- Houston, TX
- Phoenix, AZ
- Philadelphia, PA
- San Antonio, TX
- San Diego, CA
- Dallas, TX
- San Jose, CA
Pre-Test Instructions
Before scheduling your DNAH9 genetic test, please ensure you have:
- Complete clinical history of the patient
- Documentation of symptoms and previous diagnostic evaluations
- Family medical history related to respiratory and ciliary disorders
- Consider genetic counseling to discuss testing implications and create a family pedigree chart
Take Control of Your Genetic Health Today
Don’t let uncertainty about your respiratory health or family genetic risks hold you back. The DNAH9 Gene Primary Ciliary Dyskinesia NGS Genetic DNA Test provides the clarity you need for informed healthcare decisions and personalized treatment planning.
Ready to schedule your genetic test? Contact us today:
Phone: +1(267) 388-9828
WhatsApp: +1(267) 388-9828
Our genetic specialists are available to answer your questions, discuss testing options, and help you schedule your appointment at a convenient location near you. Take the first step toward understanding your genetic health and optimizing your treatment approach.
