CYP2C9 Gene Coumarin/Warfarin Resistance Due to CYP2C9 Variants NGS Genetic DNA Test
Understanding CYP2C9 Genetic Testing for Warfarin Response
The CYP2C9 Gene Coumarin/Warfarin Resistance DNA Test represents a breakthrough in personalized medicine, specifically designed to optimize anticoagulation therapy for patients requiring blood-thinning medications. This advanced genetic analysis examines variations in the CYP2C9 gene, which plays a crucial role in metabolizing coumarin-based anticoagulants like warfarin.
What Does This Test Measure?
This comprehensive NGS-based genetic test specifically detects:
- Common CYP2C9 gene variants (*2, *3, *5, *6, *8, *11) that affect warfarin metabolism
- Genetic polymorphisms influencing enzyme activity and drug clearance rates
- Specific mutations associated with warfarin resistance or hypersensitivity
- Genetic markers that predict individual response to anticoagulation therapy
Who Should Consider CYP2C9 Genetic Testing?
This test is particularly recommended for individuals experiencing:
- Unusual warfarin response requiring unusually high or low doses
- Difficulty achieving stable INR levels despite standard dosing
- History of bleeding complications while on warfarin therapy
- Family history of warfarin resistance or sensitivity
- Planned initiation of long-term anticoagulation therapy
- Recurrent thrombosis despite adequate anticoagulation
Clinical Benefits of CYP2C9 Genetic Testing
Understanding your CYP2C9 genetic profile offers numerous clinical advantages:
- Personalized Dosing: Enables precise warfarin dosing based on genetic metabolism capacity
- Reduced Complications: Minimizes risk of bleeding events and thrombotic complications
- Faster Stabilization: Accelerates achievement of therapeutic INR levels
- Improved Safety: Enhances medication safety profile through genetic-guided prescribing
- Cost-Effective Care: Reduces hospitalizations and emergency visits related to dosing issues
Understanding Your Test Results
Your CYP2C9 genetic test results will provide clear guidance on warfarin metabolism:
- Normal Metabolizer: Standard warfarin dosing typically effective
- Intermediate Metabolizer: May require lower warfarin doses and closer monitoring
- Poor Metabolizer: Significantly reduced warfarin clearance, requiring substantially lower doses
- Rapid Metabolizer: May require higher warfarin doses to achieve therapeutic effect
All results include detailed interpretation and specific dosing recommendations for your healthcare provider.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We have comprehensive testing facilities across the United States, including major metropolitan areas:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and Midwest locations
- Houston and Texas facilities
- Phoenix and Southwest centers
- And numerous additional locations nationwide
Take Control of Your Anticoagulation Therapy
Don’t leave your warfarin response to chance. Our CYP2C9 genetic testing provides the scientific foundation for safer, more effective anticoagulation management. With results available in 3-4 weeks and multiple sample collection options including blood, extracted DNA, or FTA card blood spots, getting tested has never been more convenient.
Ready to optimize your medication therapy? Book your CYP2C9 genetic test today by calling +1(267) 388-9828 or scheduling online through our secure patient portal.

