COL4A6 Gene Deafness X-Linked Type 6 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Hearing Loss
The COL4A6 Gene Deafness X-Linked Type 6 NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for hereditary hearing disorders. This advanced genetic test specifically targets mutations in the COL4A6 gene, which encodes type IV collagen alpha-6 chain, a crucial component of basement membranes in the inner ear. When this gene undergoes pathogenic mutations, it disrupts the structural integrity of cochlear basement membranes, leading to progressive sensorineural hearing loss that typically manifests in childhood or early adulthood.
What This Test Measures and Detects
Our state-of-the-art NGS Genetic DNA Test provides comprehensive analysis of:
- Complete sequencing of the COL4A6 gene to identify point mutations, insertions, and deletions
- Detection of X-linked inheritance patterns characteristic of DFNX6 deafness
- Identification of pathogenic variants affecting collagen IV alpha-6 chain production
- Assessment of mutation impact on cochlear basement membrane integrity
- Evaluation of genetic risk for progressive hearing impairment
Who Should Consider This Genetic Test
This specialized genetic test is recommended for individuals experiencing:
- Progressive sensorineural hearing loss with unknown etiology
- Family history of X-linked hearing impairment patterns
- Unexplained childhood-onset hearing deterioration
- Multiple family members affected by hearing loss across generations
- Individuals planning pregnancy with family history of genetic deafness
- Patients with suspected collagen-related hearing disorders
- Children with delayed speech development due to hearing issues
Significant Benefits of Genetic Testing
Undergoing the COL4A6 Gene Deafness X-Linked Type 6 test provides numerous advantages:
- Early Intervention Opportunities: Identify genetic predisposition before significant hearing loss occurs
- Personalized Treatment Planning: Develop targeted hearing rehabilitation strategies
- Family Planning Guidance: Understand inheritance risks for future generations
- Accurate Diagnosis: Differentiate between various types of hereditary hearing loss
- Proactive Management: Implement hearing conservation measures early
- Genetic Counseling Foundation: Provide concrete data for informed decision-making
Understanding Your Test Results
Our comprehensive genetic report provides clear, actionable information:
- Positive Result: Indicates presence of pathogenic COL4A6 mutation, confirming X-linked deafness type 6 diagnosis
- Negative Result: Suggests absence of tested COL4A6 mutations, though other genetic causes may exist
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines if individuals carry the mutation without showing symptoms
All results include detailed interpretation by our certified genetic counselors, who provide personalized recommendations for next steps, including appropriate interventions, monitoring protocols, and family testing considerations.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| COL4A6 Gene Deafness X-Linked Type 6 NGS Genetic DNA Test – Discount Price | $500 |
| COL4A6 Gene Deafness X-Linked Type 6 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic testing facilities ensures accessible, reliable testing regardless of your location.
Take Control of Your Hearing Health Today
Don’t let uncertainty about hereditary hearing loss impact your quality of life. Our COL4A6 Gene Deafness X-Linked Type 6 NGS Genetic DNA Test provides the clarity you need for informed healthcare decisions. With results available in 3-4 weeks and simple sample collection (blood, extracted DNA, or one drop of blood on FTA card), getting answers has never been easier.
Book your genetic test appointment now by calling +1(267) 388-9828 or schedule your consultation through our online booking system. Our genetic specialists are ready to guide you through the testing process and help you understand your results.
