CD59 Gene Hemolytic Anemia CD59-Mediated with or without Immune-Mediated Polyneuropathy NGS Genetic DNA Test
Comprehensive Genetic Analysis for Rare Hematological Disorders
The CD59 Gene Hemolytic Anemia NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations responsible for CD59-mediated hemolytic anemia, a rare condition that may present with or without accompanying immune-mediated polyneuropathy. This sophisticated genetic test utilizes next-generation sequencing technology to provide precise detection of pathogenic variants in the CD59 gene, enabling accurate diagnosis and personalized treatment planning.
What This Advanced Genetic Test Measures
This comprehensive NGS-based genetic test specifically targets the CD59 gene, which encodes the CD59 protein—a crucial membrane inhibitor of reactive lysis that protects cells from complement-mediated damage. The test detects:
- Pathogenic mutations in the CD59 gene coding regions
- Single nucleotide variants (SNVs) affecting protein function
- Insertions and deletions that disrupt CD59 expression
- Genetic variants associated with complement dysregulation
- Mutations leading to CD59 protein deficiency
Clinical Indications: Who Should Consider This Test
This genetic test is particularly recommended for individuals presenting with:
- Unexplained hemolytic anemia with negative direct antiglobulin test
- Recurrent episodes of intravascular hemolysis
- Neurological symptoms including peripheral neuropathy
- Family history of similar hematological or neurological conditions
- Early-onset hemolytic anemia with neurological manifestations
- Resistance to conventional hemolytic anemia treatments
- Suspected complement-mediated hemolytic disorders
Significant Benefits of Genetic Testing
Undergoing the CD59 Gene Hemolytic Anemia NGS Genetic DNA Test provides numerous clinical advantages:
- Accurate Diagnosis: Precise identification of CD59 gene mutations eliminates diagnostic uncertainty
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Prognostic Insights: Helps predict disease progression and potential complications
- Therapeutic Guidance: Informs treatment selection including complement-targeted therapies
- Early Intervention: Facilitates timely management before significant organ damage occurs
Understanding Your Genetic Test Results
Your CD59 gene test results will be carefully interpreted by our expert geneticists and hematologists:
- Positive Result: Indicates the presence of pathogenic CD59 gene mutations confirming diagnosis
- Negative Result: Suggests CD59-mediated hemolytic anemia is unlikely, directing further investigation
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals with single mutation copies who may pass the condition to offspring
All results include comprehensive genetic counseling to ensure complete understanding and appropriate next steps.
Test Pricing and Sample Requirements
| Test Component | Details | Price (USD) |
|---|---|---|
| Test Name | CD59 Gene Hemolytic Anemia CD59-Mediated with or without Immune-Mediated Polyneuropathy NGS Genetic DNA Test | – |
| Discount Price | Limited time special offer | $500 |
| Regular Price | Standard pricing | $700 |
| Turnaround Time | Comprehensive analysis period | 3-4 Weeks |
| Sample Type | Multiple collection options available | Blood, Extracted DNA, or FTA Card |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and many other cities. Our network of certified collection centers ensures accessible testing regardless of your location.
Pre-Test Preparation Requirements
To ensure optimal testing accuracy, please provide:
- Complete clinical history detailing hemolytic anemia symptoms and neurological manifestations
- Participation in genetic counseling session to create detailed family pedigree chart
- Documentation of affected family members with similar conditions
- Previous laboratory results and hematological evaluations
Take Control of Your Health Journey
Don’t let diagnostic uncertainty delay your path to appropriate treatment. Our specialized genetic testing provides the clarity needed for effective management of CD59-mediated hemolytic anemia and associated neurological conditions. With rapid turnaround times and expert genetic counseling, we ensure you receive comprehensive care and understanding of your genetic profile.
Ready to schedule your genetic test? Contact our dedicated team today at +1(267) 388-9828 or book your appointment online. Our genetic specialists are available to answer your questions and guide you through the testing process with compassion and expertise.
