B4GALNT1 Gene SPG26 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Spastic Paraplegia
The B4GALNT1 Gene SPG26 NGS Genetic DNA Test represents a significant advancement in neurological genetic diagnostics, specifically designed to identify mutations in the B4GALNT1 gene responsible for hereditary spastic paraplegia type 26 (SPG26). This sophisticated testing methodology employs next-generation sequencing (NGS) technology to provide unparalleled accuracy in detecting genetic variations associated with progressive neurological disorders affecting motor function and mobility.
What This Test Measures and Detects
This specialized genetic test focuses on comprehensive analysis of the B4GALNT1 gene, which encodes beta-1,4-N-acetyl-galactosaminyltransferase 1. The test specifically identifies:
- Pathogenic mutations in the B4GALNT1 gene associated with SPG26
- Single nucleotide variants (SNVs) and small insertions/deletions
- Copy number variations affecting gene function
- Autosomal recessive inheritance patterns
- Specific genetic markers linked to progressive spastic paraplegia
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing the following symptoms or circumstances:
- Progressive muscle stiffness and spasticity in lower limbs
- Difficulty walking or gait abnormalities developing in childhood or early adulthood
- Family history of hereditary spastic paraplegia or similar neurological conditions
- Unexplained progressive weakness in leg muscles
- Children showing delayed motor development with spasticity
- Individuals with consanguineous parents and neurological symptoms
- Patients undergoing differential diagnosis for various forms of spastic paraplegia
Significant Benefits of B4GALNT1 Genetic Testing
Undergoing the B4GALNT1 Gene SPG26 NGS Genetic DNA Test provides numerous clinical advantages:
- Accurate Diagnosis: Provides definitive identification of SPG26, enabling precise neurological condition classification
- Family Planning Guidance: Offers crucial information for genetic counseling and reproductive decision-making
- Treatment Planning: Helps neurologists develop targeted management strategies for symptom control
- Prognostic Information: Provides insights into disease progression and expected clinical course
- Early Intervention: Facilitates timely implementation of physical therapy and supportive care
- Genetic Confirmation: Eliminates diagnostic uncertainty and reduces unnecessary additional testing
Understanding Your Test Results
Our comprehensive genetic counseling support helps you interpret your B4GALNT1 gene test results:
- Positive Result: Indicates identified pathogenic mutations in the B4GALNT1 gene, confirming SPG26 diagnosis
- Negative Result: Suggests absence of detectable B4GALNT1 mutations, though other genetic causes should be considered
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Determines if individuals carry one copy of a mutated gene without showing symptoms
All results are accompanied by detailed explanations and recommendations from our genetic specialists to ensure complete understanding and appropriate next steps.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| B4GALNT1 Gene SPG26 NGS Genetic DNA Test – Discount Price | $500 |
| B4GALNT1 Gene SPG26 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other cities. Our extensive network ensures accessible genetic testing services regardless of your location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about hereditary neurological conditions affect your quality of life. Our B4GALNT1 Gene SPG26 NGS Genetic DNA Test provides the answers you need for informed medical decisions and comprehensive care planning.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and testing appointment. Our dedicated genetic specialists are ready to guide you through the testing process and help you understand your results with compassion and expertise.
With a turnaround time of 3-4 weeks and multiple sample collection options including blood, extracted DNA, or FTA card blood spots, we make genetic testing convenient and accessible. Take control of your neurological health with definitive genetic answers from America’s trusted genetics laboratory.
