ARSI Gene SPG66 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Spastic Paraplegia
The ARSI Gene SPG66 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, specifically designed to identify mutations in the ARSI gene responsible for hereditary spastic paraplegia type 66 (SPG66). This advanced next-generation sequencing technology provides unparalleled accuracy in detecting genetic variants that contribute to progressive neurological conditions affecting motor function and mobility.
What Does This Test Measure?
This sophisticated genetic analysis specifically targets the ARSI (arylsulfatase family member I) gene, which plays a critical role in cellular metabolism and neurological function. The test utilizes next-generation sequencing technology to:
- Identify pathogenic variants and mutations in the ARSI gene
- Detect single nucleotide polymorphisms (SNPs) associated with SPG66
- Analyze gene copy number variations
- Assess potential compound heterozygous mutations
- Provide comprehensive coverage of all coding regions and splice sites
Who Should Consider ARSI Gene Testing?
This genetic test is particularly recommended for individuals experiencing:
- Progressive leg stiffness and spasticity
- Difficulty walking or changes in gait pattern
- Muscle weakness in lower extremities
- Family history of hereditary spastic paraplegia
- Unexplained neurological symptoms beginning in childhood or early adulthood
- Developmental delays with progressive motor impairment
- Abnormal reflexes and increased muscle tone
Clinical Benefits of ARSI Gene Testing
Undergoing ARSI Gene SPG66 testing provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms or rules out SPG66 with high precision
- Early Intervention: Enables proactive management strategies
- Family Planning: Provides crucial information for genetic counseling
- Personalized Treatment: Guides targeted therapeutic approaches
- Prognostic Information: Helps predict disease progression
- Research Contribution: Advances understanding of rare neurological disorders
Understanding Your Test Results
Your ARSI Gene SPG66 test results will be carefully interpreted by our team of genetic specialists and neurologists. Results typically fall into three categories:
- Positive Result: Indicates the presence of pathogenic ARSI gene mutations associated with SPG66. This confirms the diagnosis and enables targeted management strategies.
- Negative Result: Suggests no detectable ARSI gene mutations were found, though other genetic or non-genetic causes should still be considered.
- Variant of Uncertain Significance (VUS): Identifies genetic changes whose clinical significance is currently unknown, requiring ongoing monitoring and potential family studies.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | ARSI Gene SPG66 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) |
Pre-Test Preparation
For optimal results, we recommend:
- Comprehensive clinical history documentation of neurological symptoms
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Testing Availability
GGC DNA provides comprehensive genetic testing services across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality results regardless of your location.
Take Control of Your Neurological Health
Don’t let uncertainty about hereditary spastic paraplegia affect your quality of life. The ARSI Gene SPG66 NGS Genetic DNA Test provides the clarity needed for informed medical decisions and personalized care planning. Our team of genetic specialists and neurologists are committed to supporting you through every step of the testing process.
Ready to schedule your genetic test? Contact us today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic health and accessing targeted treatment options for hereditary neurological conditions.
