ARFGEF2 Gene Periventricular Heterotopia with Microcephaly NGS Genetic DNA Test
Comprehensive Genetic Testing for Neurological Development Disorders
The ARFGEF2 Gene Periventricular Heterotopia with Microcephaly NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, providing definitive answers for individuals and families affected by complex brain development disorders. This advanced genetic analysis specifically targets mutations in the ARFGEF2 gene, which plays a critical role in neuronal migration and brain formation during embryonic development.
What Does This Test Measure and Detect?
This comprehensive genetic test utilizes Next Generation Sequencing (NGS) technology to thoroughly analyze the ARFGEF2 gene for pathogenic variants associated with:
- Point mutations, insertions, and deletions in the ARFGEF2 gene
- Genetic variations causing periventricular heterotopia (neurons failing to migrate properly)
- Mutations leading to microcephaly (abnormally small head size)
- Inherited and de novo genetic changes affecting brain development
- Specific nucleotide changes impacting protein function and neuronal migration
Who Should Consider This Genetic Test?
This specialized genetic testing is recommended for individuals presenting with:
- Developmental delays and intellectual disability of unknown origin
- Recurrent seizures or epilepsy with unclear etiology
- Microcephaly (head circumference below the 3rd percentile)
- Family history of neurological developmental disorders
- Abnormal brain MRI findings showing periventricular heterotopia
- Unexplained neurological symptoms in infancy or childhood
- Previous inconclusive genetic testing results
Key Benefits of ARFGEF2 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Definitive Diagnosis: Obtain clear answers about the genetic cause of neurological symptoms
- Personalized Treatment: Guide medication choices and therapeutic interventions based on genetic findings
- Family Planning: Understand inheritance patterns and recurrence risks for future pregnancies
- Early Intervention: Enable timely implementation of developmental support services
- Genetic Counseling: Provide accurate information for making informed medical decisions
- Research Contribution: Help advance scientific understanding of neurological genetic disorders
Understanding Your Test Results
Our comprehensive genetic counseling services help you interpret your results:
- Positive Result: Indicates a pathogenic mutation in the ARFGEF2 gene, confirming the genetic diagnosis and enabling targeted management strategies
- Negative Result: Suggests no mutation detected in the ARFGEF2 gene, though other genetic causes may need investigation
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical implications, requiring ongoing monitoring and family studies
- Carrier Status: Determines if individuals carry one copy of a mutated gene, important for family planning decisions
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | ARFGEF2 Gene Periventricular Heterotopia with Microcephaly NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation of the patient
- Genetic counseling session to create a detailed family pedigree chart
- Documentation of family members affected with similar neurological conditions
- Previous medical records and imaging studies (MRI, CT scans)
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and neurological specialists ensures you receive comprehensive care regardless of your location.
Take the Next Step Toward Answers
Don’t let uncertainty about neurological symptoms continue. Our ARFGEF2 genetic testing provides the clarity needed for proper diagnosis and management. With our discounted price of $500 USD and comprehensive genetic counseling support, you can make informed decisions about your health or your family’s health.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
