AMELX Gene Amelogenesis Imperfecta Type 1E NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Dental Enamel Defects
The AMELX Gene Amelogenesis Imperfecta Type 1E NGS Genetic DNA Test represents a breakthrough in dental genetic diagnostics, offering precise identification of mutations responsible for hereditary enamel formation disorders. This advanced testing methodology provides families and healthcare providers with critical information for managing and treating Amelogenesis Imperfecta, a condition that affects tooth development and quality from birth.
What Does This Test Measure and Detect?
Our specialized genetic test focuses on comprehensive analysis of the AMELX gene using Next-Generation Sequencing technology to identify:
- Point mutations and single nucleotide variations in the AMELX gene
- Small insertions and deletions affecting enamel protein production
- Genetic markers associated with X-linked Amelogenesis Imperfecta Type 1E
- Specific variations that disrupt amelogenin protein function
- Inheritance patterns for genetic counseling purposes
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals and families experiencing:
- Family history of hereditary dental enamel defects
- Discolored, yellow, or brown teeth from early childhood
- Extreme tooth sensitivity to temperature changes
- Rapid tooth wear and enamel erosion
- Multiple dental restorations at young ages
- Unexplained tooth fractures and structural weaknesses
- Planning for pregnancy with family history of enamel disorders
Clinical Benefits of AMELX Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Early Intervention Planning: Enables proactive dental care strategies before severe damage occurs
- Personalized Treatment: Guides dentists in selecting appropriate restorative materials and techniques
- Genetic Counseling: Provides accurate inheritance risk assessment for family planning
- Differential Diagnosis: Distinguishes between genetic and environmental causes of enamel defects
- Preventive Care: Facilitates targeted preventive measures to preserve remaining enamel
- Psychological Relief: Offers clarity and understanding of the condition’s genetic basis
Understanding Your Test Results
Our comprehensive genetic report provides clear, actionable information:
- Positive Result: Indicates presence of AMELX gene mutation; confirms diagnosis of Amelogenesis Imperfecta Type 1E
- Negative Result: Suggests absence of tested AMELX mutations; other genetic or environmental factors may be considered
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact; requires follow-up monitoring
- Carrier Status: For family members, identifies individuals who may pass the condition to offspring
All results include detailed interpretation by our genetic specialists and recommendations for next steps in dental care and genetic counseling.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | AMELX Gene Amelogenesis Imperfecta Type 1E NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and Philadelphia. Our network ensures accessible genetic testing services for families nationwide.
Take Control of Your Dental Health Today
Don’t let hereditary dental conditions impact your quality of life. Our AMELX genetic testing provides the clarity needed for effective dental management and family planning. Schedule your consultation and genetic testing appointment today to gain valuable insights into your dental health inheritance patterns.
Call or WhatsApp us now at +1(267) 388-9828 to book your AMELX Gene Amelogenesis Imperfecta Type 1E NGS Genetic DNA Test and take the first step toward comprehensive dental genetic understanding.
