AMBN Gene Amelogenesis Imperfecta Type 1F NGS Genetic DNA Test
Comprehensive Genetic Testing for Enamel Development Disorders
The AMBN Gene Amelogenesis Imperfecta Type 1F NGS Genetic DNA Test represents a breakthrough in dental genetic diagnostics, offering precise identification of mutations in the AMBN (Ameloblastin) gene that cause Amelogenesis Imperfecta Type 1F. This autosomal recessive condition disrupts normal enamel formation during tooth development, resulting in significant dental complications that can impact both oral health and quality of life.
What Does This Test Measure and Detect?
Our advanced NGS (Next-Generation Sequencing) technology provides comprehensive analysis of the AMBN gene to identify:
- Pathogenic variants and mutations in the AMBN gene
- Single nucleotide polymorphisms (SNPs) affecting enamel formation
- Deletions, insertions, and other structural variations
- Autosomal recessive inheritance patterns
- Specific genetic markers associated with Type 1F Amelogenesis Imperfecta
The test examines the complete coding region of the AMBN gene, which encodes the ameloblastin protein essential for proper enamel matrix organization and mineralization during tooth development.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Family history of enamel defects or dental abnormalities
- Discolored, yellow, or brown teeth from childhood
- Extreme tooth sensitivity to temperature changes
- Rapid tooth wear and enamel erosion
- Abnormal tooth shape or size variations
- Multiple dental restorations at a young age
- Unexplained dental caries despite good oral hygiene
- Planning for pregnancy with family history of enamel disorders
Clinical Benefits of AMBN Genetic Testing
Undergoing AMBN gene testing provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms or rules out genetic causes of enamel defects
- Personalized Treatment Planning: Guides appropriate dental interventions and preventive care
- Family Planning Guidance: Provides information about inheritance risks for future generations
- Early Intervention: Enables proactive dental management from childhood
- Psychological Relief: Offers clarity and understanding of the condition’s genetic basis
- Comprehensive Care Coordination: Facilitates collaboration between geneticists and dental specialists
Understanding Your Test Results
Our genetic counseling team provides comprehensive interpretation of your AMBN gene test results:
- Positive Result: Indicates the presence of pathogenic AMBN gene mutations confirming Amelogenesis Imperfecta Type 1F diagnosis
- Negative Result: Suggests that AMBN gene mutations are not detected, though other genetic causes may need investigation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further evaluation
- Carrier Status: Determines if you carry one copy of the mutated gene without showing symptoms
All results include detailed explanations and recommendations for next steps in dental care and genetic counseling.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | AMBN Gene Amelogenesis Imperfecta Type 1F NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Genetic Dentistry, Dermatology, Genetics |
Pre-Test Requirements
Before scheduling your AMBN gene test, we recommend:
- Complete clinical history documentation
- Genetic counseling session to discuss testing implications
- Development of a family pedigree chart documenting affected relatives
- Discussion of potential outcomes and their implications
- Informed consent process understanding benefits and limitations
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities. Our network of certified collection centers ensures accessible testing regardless of your location.
Take Control of Your Dental Health Today
Don’t let uncertainty about enamel disorders affect your quality of life. Our AMBN Gene Amelogenesis Imperfecta Type 1F NGS Genetic DNA Test provides the clarity you need for informed dental care decisions and family planning. With our special discounted price of only $500 USD, comprehensive genetic testing has never been more accessible.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
