ABCC8 Gene Diabetes Mellitus Transient Neonatal Type 2 NGS Genetic DNA Test
Comprehensive Genetic Testing for Transient Neonatal Diabetes
The ABCC8 Gene Diabetes Mellitus Transient Neonatal Type 2 NGS Genetic DNA Test represents a breakthrough in pediatric genetic diagnostics, specifically designed to identify mutations in the ABCC8 gene that cause transient neonatal diabetes mellitus type 2. This sophisticated genetic analysis provides critical insights for families and healthcare providers managing diabetes in newborns, enabling precise diagnosis and targeted treatment approaches.
What This Advanced Genetic Test Detects
Our NGS-based genetic test specifically targets the ABCC8 gene, which encodes the sulfonylurea receptor 1 (SUR1) subunit of the ATP-sensitive potassium channel in pancreatic beta cells. Mutations in this gene disrupt normal insulin secretion mechanisms, leading to transient hyperglycemia in neonates. The test comprehensively analyzes:
- Point mutations and small insertions/deletions in the ABCC8 gene
- Genetic variations affecting potassium channel function
- Mutations that impair insulin secretion regulation
- Genetic markers associated with transient neonatal diabetes susceptibility
Who Should Consider This Genetic Test
This specialized genetic test is recommended for newborns and infants presenting with specific clinical indications:
- Infants diagnosed with diabetes within the first 6 months of life
- Newborns with persistent hyperglycemia requiring insulin therapy
- Babies with intrauterine growth restriction and subsequent diabetes diagnosis
- Infants with family history of neonatal diabetes or similar metabolic disorders
- Cases where transient neonatal diabetes is suspected but not confirmed
Clinical Benefits of Genetic Testing
Early genetic diagnosis through ABCC8 gene testing offers numerous advantages for patient care and family planning:
- Precise Diagnosis: Differentiates transient neonatal diabetes from permanent forms and other metabolic disorders
- Personalized Treatment: Enables transition from insulin to sulfonylurea therapy when appropriate
- Prognostic Information: Helps predict the likelihood of diabetes remission and potential recurrence
- Family Counseling: Provides valuable information for genetic counseling and recurrence risk assessment
- Early Intervention: Facilitates timely management strategies to prevent complications
Understanding Your Genetic Test Results
Our comprehensive genetic report provides clear, actionable information:
- Positive Result: Identifies a pathogenic mutation in the ABCC8 gene, confirming the genetic basis of transient neonatal diabetes
- Negative Result: No mutation detected in the ABCC8 gene, suggesting other genetic or non-genetic causes
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical significance requiring further evaluation
- Carrier Status: Determines if parents carry the mutation, important for family planning
All results are accompanied by detailed interpretation and recommendations from our genetic specialists.
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | ABCC8 Gene Diabetes Mellitus Transient Neonatal Type 2 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services for families nationwide.
Take the Next Step Toward Genetic Clarity
If your infant is experiencing symptoms suggestive of transient neonatal diabetes or has a family history of similar conditions, don’t wait to get answers. Our ABCC8 gene testing provides the genetic clarity needed for optimal medical management and family planning decisions.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book the ABCC8 Gene Diabetes Mellitus Transient Neonatal Type 2 NGS Genetic DNA Test. Our genetic specialists are ready to guide you through the testing process and help you understand the implications of your results for your child’s health and future.
