ABCB4 Gene Cholestasis Progressive Intrahepatic Type 3 NGS Genetic DNA Test
Comprehensive Genetic Testing for Progressive Liver Disorders
The ABCB4 Gene Cholestasis Progressive Intrahepatic Type 3 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with progressive familial intrahepatic cholestasis type 3 (PFIC3). This specialized genetic analysis utilizes next-generation sequencing technology to provide comprehensive insights into inherited liver conditions that affect bile production and flow, potentially leading to severe liver complications if left undiagnosed.
What This Advanced Genetic Test Measures
This sophisticated diagnostic test specifically targets the ABCB4 gene, which encodes the multidrug resistance protein 3 (MDR3) crucial for proper bile formation. The test detects:
- Pathogenic variants and mutations in the ABCB4 gene
- Single nucleotide polymorphisms associated with PFIC3
- Deletions, insertions, and complex rearrangements affecting gene function
- Genetic markers indicating susceptibility to progressive liver damage
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Unexplained persistent jaundice or yellowing of skin and eyes
- Chronic itching (pruritus) without apparent cause
- Elevated liver enzymes in blood tests
- Family history of liver disorders or cholestatic conditions
- Progressive liver dysfunction in childhood or early adulthood
- Failed response to conventional liver disease treatments
Significant Benefits of Genetic Testing
Undergoing the ABCB4 genetic test provides numerous advantages:
- Early Diagnosis: Enables timely intervention before significant liver damage occurs
- Personalized Treatment: Guides targeted therapeutic approaches based on genetic profile
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Disease Management: Helps monitor disease progression and adjust treatment strategies
- Peace of Mind: Reduces uncertainty and provides clear diagnostic information
Understanding Your Test Results
Our comprehensive genetic analysis provides detailed insights into your ABCB4 gene status:
- Positive Result: Indicates the presence of pathogenic mutations associated with PFIC3, requiring specialized medical management
- Negative Result: Suggests no detected mutations in the ABCB4 gene, though clinical correlation remains essential
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical evaluation and family studies
All results are accompanied by detailed interpretation from our genetic specialists, ensuring you receive comprehensive guidance for next steps.
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Control of Your Liver Health Today
Don’t let uncertainty about your liver health continue. Our ABCB4 Gene Cholestasis Progressive Intrahepatic Type 3 NGS Genetic DNA Test provides the clarity you need for informed medical decisions. With results available in 3-4 weeks and comprehensive genetic counseling support, you’ll have the information necessary to manage your health effectively.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment. Our dedicated genetic specialists are ready to answer your questions and guide you through the testing process.
