A2M Gene Alpha-2-Macroglobulin Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Metabolic Health
The A2M Gene Alpha-2-Macroglobulin Deficiency NGS Genetic DNA Test represents a significant advancement in genetic diagnostics for metabolic disorders. This specialized test utilizes state-of-the-art Next-Generation Sequencing (NGS) technology to identify mutations in the A2M gene, which encodes alpha-2-macroglobulin—a crucial plasma protein involved in proteinase inhibition and immune regulation.
What This Test Measures and Detects
This comprehensive genetic analysis specifically targets:
- Complete sequencing of the A2M gene to identify pathogenic variants
- Detection of single nucleotide polymorphisms (SNPs) associated with alpha-2-macroglobulin deficiency
- Identification of insertions, deletions, and copy number variations affecting gene function
- Assessment of genetic markers linked to impaired proteinase inhibition capacity
Who Should Consider This Test
This genetic test is particularly recommended for individuals experiencing:
- Unexplained recurrent infections or chronic inflammatory conditions
- Family history of alpha-2-macroglobulin deficiency or related metabolic disorders
- Abnormal proteinase inhibitor levels in blood tests
- Unexplained connective tissue abnormalities or joint problems
- Planning for pregnancy with family history of metabolic conditions
Key Benefits of Genetic Testing
- Early Diagnosis: Enables timely intervention before significant symptoms develop
- Personalized Treatment: Guides targeted therapeutic approaches based on genetic profile
- Family Planning: Provides crucial information for reproductive decision-making
- Risk Assessment: Helps identify at-risk family members for preventive care
- Peace of Mind: Offers clarity and reduces diagnostic uncertainty
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and physicians:
- Positive Result: Indicates the presence of pathogenic variants associated with alpha-2-macroglobulin deficiency. Our genetic counseling team will provide comprehensive guidance on management strategies and family screening recommendations.
- Negative Result: Suggests no detectable mutations in the A2M gene, significantly reducing the likelihood of inherited alpha-2-macroglobulin deficiency.
- Variant of Uncertain Significance (VUS): Some genetic changes may require additional family studies or research correlation for definitive interpretation.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | A2M Gene Alpha-2-Macroglobulin Deficiency NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood |
| Testing Method | NGS Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create a detailed family pedigree chart
- Discussion of testing implications with our genetic specialists
- Understanding of potential outcomes and their significance
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities nationwide. Our network of certified genetic testing centers ensures accessible, high-quality care regardless of your location.
Take Control of Your Genetic Health Today
Don’t let uncertainty about your genetic health hold you back. Our A2M Gene Alpha-2-Macroglobulin Deficiency NGS Genetic DNA Test provides the clarity and confidence you need to make informed healthcare decisions. With our discounted price of only $500 USD and comprehensive genetic counseling support, you’re investing in your long-term health and wellbeing.
Ready to schedule your genetic test? Contact our dedicated genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic profile and optimizing your metabolic health.
