1p 19q Test: Comprehensive Chromosomal Analysis for Brain Tumor Diagnosis
Understanding the 1p 19q Genetic Test
The 1p 19q Test represents a groundbreaking advancement in neuro-oncology diagnostics, providing critical genetic information that directly impacts treatment decisions and prognosis for patients with brain tumors. This specialized test examines specific chromosomal regions to identify genetic alterations that define certain types of gliomas, particularly oligodendrogliomas.
What Does the 1p 19q Test Measure?
This sophisticated genetic analysis specifically detects co-deletions of chromosomal arms 1p and 19q using Fluorescence In Situ Hybridization (FISH) technology. The test evaluates:
- Deletion status of chromosome 1p (short arm)
- Deletion status of chromosome 19q (long arm)
- Presence of combined 1p/19q co-deletion
- Genetic markers for oligodendroglial tumors
Clinical Importance and Applications
The 1p 19q co-deletion serves as a definitive molecular marker that distinguishes oligodendrogliomas from other glioma subtypes. This genetic signature has profound implications for:
- Tumor Classification: Accurate diagnosis of oligodendroglioma versus astrocytoma
- Treatment Response Prediction: Enhanced sensitivity to chemotherapy and radiation
- Prognostic Assessment: Improved survival outcomes with 1p/19q co-deleted tumors
- Therapeutic Decision Making: Guidance for personalized treatment approaches
Who Should Consider This Test?
This test is particularly valuable for patients presenting with:
- Suspected oligodendroglioma based on imaging studies
- Mixed glioma tumors requiring precise classification
- Recurrent brain tumors needing molecular characterization
- Patients considering chemotherapy or radiation treatment
- Those seeking comprehensive genetic profiling of CNS tumors
Key Benefits of 1p 19q Testing
Undergoing 1p 19q chromosomal analysis offers multiple advantages:
- Precise Diagnosis: Confirms oligodendroglioma diagnosis with molecular evidence
- Treatment Optimization: Guides selection of most effective therapies
- Prognostic Clarity: Provides insight into expected treatment outcomes
- Personalized Care: Enables tailored treatment plans based on genetic profile
- Clinical Trial Eligibility: May qualify patients for targeted therapy trials
Test Specifications and Requirements
Sample Type: Tumor tissue (paraffin-embedded tissue blocks)
Methodology: Fluorescence In Situ Hybridization (FISH)
Turnaround Time: 7-8 days
Prescription Requirements: Doctor’s prescription required (not applicable for surgery, pregnancy, or international travel cases)
Understanding Your Test Results
Your 1p 19q test results will fall into one of several categories:
- 1p/19q Co-deletion Present: Indicates oligodendroglioma with favorable prognosis and better response to treatment
- No Co-deletion Detected: Suggests other glioma subtypes requiring different treatment approaches
- Partial Deletion: May indicate mixed glioma or require additional testing
- Inconclusive Results: May necessitate repeat testing or alternative methods
All results should be discussed with your healthcare provider in the context of your complete clinical picture, including imaging findings and pathology reports.
Test Pricing and Booking Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $300 |
| Regular Price | $400 |
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services nationwide.
Take Action for Your Brain Health
Don’t leave your diagnosis to chance. The 1p 19q Test provides the genetic clarity needed for informed treatment decisions and optimal outcomes. Our experienced genetic counselors and oncology specialists are ready to guide you through the testing process and help interpret your results.
Ready to schedule your 1p 19q Test? Contact our dedicated patient care team today at +1(267) 388-9828 or book your appointment online. Take the first step toward personalized brain tumor care with definitive genetic testing.
