HLA DNA Typing for Bone Marrow Transplant 6 Antigens Luminex Test
Comprehensive Introduction to HLA DNA Typing
The HLA DNA Typing for Bone Marrow Transplant 6 Antigens Luminex Test represents a cornerstone of modern transplantation medicine, providing essential genetic compatibility information for successful bone marrow transplantation procedures. This sophisticated molecular diagnostic test evaluates six critical human leukocyte antigens (HLA) that play a pivotal role in immune system recognition and response. The precision of HLA matching directly correlates with transplant success rates, making this test an indispensable component of pre-transplant evaluation protocols.
What This Test Measures and Detects
Our advanced Luminex-based test specifically targets and analyzes six key HLA antigens through comprehensive DNA typing:
- HLA-A Antigens: Critical class I molecules that present intracellular antigens to cytotoxic T-cells
- HLA-B Antigens: Additional class I antigens essential for immune surveillance and viral defense
- HLA-DR Antigens: Class II molecules that regulate immune responses and antigen presentation
The test employs Reverse Sequence Specific Oligonucleotide Probe (Reverse SSOP) methodology using Luminex technology, providing high-resolution genetic data for accurate donor-recipient matching.
Who Should Consider This Test
This specialized HLA typing test is recommended for individuals in the following clinical scenarios:
- Patients diagnosed with hematological malignancies requiring bone marrow transplantation
- Individuals with inherited blood disorders such as sickle cell anemia or thalassemia
- Patients with severe aplastic anemia or other bone marrow failure syndromes
- Those undergoing evaluation for allogeneic stem cell transplantation
- Family members being screened as potential bone marrow donors
- Patients with autoimmune diseases considering hematopoietic stem cell transplantation
Significant Benefits of HLA DNA Typing
Undergoing comprehensive HLA typing provides numerous clinical advantages:
- Enhanced Transplant Success: Precise HLA matching significantly improves engraftment rates and reduces rejection risks
- Reduced Graft-versus-Host Disease: Better HLA compatibility minimizes the risk of this serious transplant complication
- Improved Long-term Outcomes: Well-matched transplants demonstrate superior survival rates and quality of life
- Informed Donor Selection: Enables healthcare providers to identify the most suitable donor from available options
- Personalized Treatment Planning: Guides immunosuppression protocols and post-transplant monitoring strategies
Understanding Your Test Results
Your HLA typing results will provide detailed information about your genetic profile:
- HLA Allele Identification: Specific genetic variants detected for each of the six antigens tested
- Compatibility Scoring: Assessment of how well your HLA profile matches potential donors
- Clinical Interpretation: Expert analysis of what your results mean for transplantation success
- Donor Matching Guidance: Recommendations for optimal donor selection based on your genetic profile
Results are typically available within 10-12 days and will be thoroughly explained by our genetic counseling team.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $432 |
| Regular Price | $482 |
Nationwide Accessibility
We maintain comprehensive testing facilities across major metropolitan areas throughout the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to this critical testing service regardless of your location.
Take the Next Step Toward Transplantation Success
Don’t leave your transplant success to chance. Our HLA DNA Typing for Bone Marrow Transplant 6 Antigens Luminex Test provides the essential genetic information needed for optimal donor matching and improved transplantation outcomes. With rapid 10-12 day turnaround and comprehensive analysis of six critical HLA antigens, this test represents the gold standard in transplantation compatibility assessment.
Ready to schedule your test? Call us today at +1(267) 388-9828 or book your appointment online to begin your journey toward successful bone marrow transplantation.
