CUL4B Gene Mental Retardation X-Linked Type 15 NGS Genetic DNA Test
Comprehensive Genetic Testing for X-Linked Intellectual Disability
The CUL4B Gene Mental Retardation X-Linked Type 15 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise detection of mutations associated with X-linked intellectual disability syndrome. This advanced testing methodology provides families and healthcare providers with definitive answers about inherited neurological conditions that affect cognitive development and neurological function.
What This Test Measures and Detects
Our specialized NGS genetic test specifically targets the CUL4B gene located on the X chromosome, which plays a critical role in protein degradation and neuronal development. The test identifies:
- Pathogenic mutations in the CUL4B gene sequence
- Single nucleotide variants (SNVs) and small insertions/deletions
- Copy number variations affecting the CUL4B gene region
- X-linked inheritance patterns consistent with mental retardation type 15
- Genetic markers associated with progressive neurological deterioration
Who Should Consider This Genetic Test
This comprehensive genetic evaluation is recommended for individuals presenting with:
- Unexplained intellectual disability or developmental delays
- Family history of X-linked mental retardation
- Progressive neurological symptoms including ataxia and tremors
- Characteristic facial features associated with CUL4B syndrome
- Behavioral abnormalities and social interaction difficulties
- Muscle weakness or hypotonia in childhood
- Seizures or epilepsy of unknown origin
- Delayed speech and language development
Clinical Benefits of CUL4B Genetic Testing
Undergoing this specialized genetic test provides numerous advantages for patients and families:
- Accurate Diagnosis: Provides definitive identification of CUL4B-related mental retardation
- Family Planning Guidance: Enables informed reproductive decisions for carriers
- Personalized Treatment: Guides targeted therapeutic interventions and management strategies
- Prognostic Information: Helps predict disease progression and potential complications
- Genetic Counseling: Supports comprehensive family risk assessment and education
- Early Intervention: Facilitates timely implementation of developmental support services
Understanding Your Test Results
Our genetic specialists provide comprehensive interpretation of your CUL4B gene test results:
- Positive Result: Indicates the presence of a pathogenic CUL4B mutation, confirming diagnosis of X-linked mental retardation type 15
- Negative Result: Suggests absence of detectable CUL4B mutations, though other genetic causes should be considered
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: For female relatives, determines risk of passing the condition to offspring
All results include detailed clinical correlation and recommendations for follow-up care from our board-certified genetic counselors.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| CUL4B Gene Mental Retardation X-Linked Type 15 NGS Genetic DNA Test | $700 |
| Discount Price | $500 |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about neurological symptoms or family history prevent you from getting the answers you need. Our experienced genetic counselors and neurologists are ready to help you understand your genetic risks and develop appropriate management strategies.
Call us today at +1(267) 388-9828 to schedule your CUL4B genetic test consultation or book your appointment online. Take control of your genetic health with comprehensive, accurate testing from America’s leading neurological genetics specialists.
